Post Doctoral Fellow - Cardiometabolic Renal Disease Research

BioCT Innovation Commons; Ridgefield (CT); On-site; USD 72,000 - 88,000; Full time

Job summary

Boehringer Ingelheim is seeking a Postdoctoral Fellow to join the Cardiometabolic Renal Disease Research (CRMDR) Department at our US headquarters in Ridgefield, CT. The role focuses on developing translational human CKD models to uncover cellular mechanisms and therapeutic opportunities, with three-year terms and potential extension.

You will work under an experienced PI, publish in leading journals, and present findings to leadership, contributing to a growing pipeline and global collaboration

Qualifications

• Ph.D. required in Biology/Pharmacology or related field; preference for <=3 years postdoc.
• Experience with qPCR and gene expression analysis.
• Experience with protein-based assays (Western blot, ELISA, MSD).
• Experience with fluorescence microscopy and immunocytochemistry/immunofluorescence.
• Genetic perturbation methods including siRNA, CRISPR, lentiviral transduction or overexpression systems.

Responsibilities

• Design and conduct independent research projects.
• Collaborate with researchers within and outside Boehringer Ingelheim.
• Communicate work clearly in oral and written form.

Skills

qPCR

gene expression analysis

protein-based assays

fluorescence microscopy

immunocytochemistry/immunofluorescence

CRISPR / siRNA

data analysis

independent research

scientific communication

Education

Ph.D. in Biology/Pharmacology or related

Tools

Western blotting

ELISA

MSD

RNA sequencing

Job description

Compensation Data

The base salary for this position is $80,000.00 USD. The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please click here.

Description

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides an opportunity for all employees to collaborate internationally, offering visibility and the opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Boehringer Ingelheim is seeking an enthusiastic, creative, and highly motivated Postdoctoral Fellow to join the Cardiometabolic Renal Disease Research (CRMDR) Department at our US headquarters in Ridgefield, CT. The Ridgefield campus, along with our sister sites in Texas and California, includes a thriving community of postdocs and PhD students that connects globally with their peers on our European campuses. The main responsibility of this position is to develop and validate translationally relevant human in vitro chronic kidney disease (CKD) models to uncover the cellular mechanisms and therapeutic opportunities underlying CKD progression.

As a Postdoctoral Fellow, you will be responsible for conducting independent research under the direct guidance of an experienced Principal Investigator and further supported by a team of experts committed to your success. You will interact with a diverse range of individuals (including mentors, fellow researchers, students, and collaborators from various institutions), and help to foster a collaborative research environment that facilitates exchange of knowledge and ideas. Your research will be focused on fundamental scientific questions and new methodologies that align with the goals of the department and contribute to Boehringer-Ingelheim's innovative and growing pipeline. You will be expected to present your work to internal leadership and, ultimately, publish your findings in leading journals within the field. Postdoctoral Fellowships are three-year positions, with a potential one-year extension.

Duties & Responsibilities

With support from their advisor and team, the ideal candidate is expected to:

• Design and conduct their own independent research project(s).
• Collaborate with other researchers within and outside Boehringer Ingelheim.
• Effectively communicate and defend their own work in the context of team and department goals, both orally and in writing.
• Establish an international reputation in your area of expertise with publications and conference participation at national and international events.
• Publish first-author manuscript(s) and/or patenting of novel technologies/processes.
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies.

Requirements

• Ph.D. degree in Biology, Pharmacology or related discipline, with a preference of no more than three (3) years of previous Post Doctoral experience.
• Experience performing qPCR and gene expression analysis
• Experience with protein-based assays (western blotting, ELISA, MSD or similar)
• Experience with fluorescence microscopy and immunocytochemistry/immunofluorescence
• Experience with genetic perturbation approaches including siRNA, CRISPR, lentiviral transduction or overexpression systems
• Ability to think and plan strategically as well as tactically.
• Creativity and innovation in driving cutting-edge research with a strong publication record.
• Ability to independently conduct a research project and effectively communicate the results.
• Experience in data analysis.
• Comfortable designing and executing independent experiments
• Demonstrated ability to analyze, interpret, and present complex biological datasets
• Strong scientific communication skills, including manuscript and presentation preparation
• Evidence of productivity through peer-reviewed publications and/or conference presentations
• Ability to work independently while collaborating effectively within multidisciplinary teams
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies.

Eligibility Requirements

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required).
• Must be 18 years of age or older.

Desired Skills, Experience and Abilities

• Previous research experience in chronic kidney disease, renal fibrosis, metabolic disease or tissue injury/repair biology
• Experience with:
  • Primary cell culture (human primary cells preferred)
  • Transwell® permeable membrane culture systems
  • Co-culture or multicellular model systems
  • RNA sequencing and transcriptomic data interpretation
  • Bioinformatics analysis including differential expression, pathway enrichment and clustering approaches
  • High-content imagers and image analysis tools