Post Doctoral Fellow - Cardiometabolic Renal Disease Research

Boehringer Ingelheim; Ridgefield (CT); On-site; USD 72,000 - 88,000; Full time

Job summary

Boehringer Ingelheim is seeking a Postdoctoral Fellow to join the Cardiometabolic Renal Disease Research (CRMDR) Department at the US headquarters in Ridgefield, CT. Develop and validate human in vitro CKD models to uncover cellular mechanisms and therapeutic opportunities while collaborating across global teams.

The role involves independent research under an experienced PI, presenting at internal leadership meetings, and targeting publications in leading journals.

Qualifications

• Ph.D. in Biology, Pharmacology or related discipline, with a preference of no more than three (3) years of previous Post Doctoral experience
• Experience performing qPCR and gene expression analysis
• Experience with protein-based assays (western blotting, ELISA, MSD or similar)
• Experience with fluorescence microscopy and immunocytochemistry/immunofluorescence
• Experience with genetic perturbation approaches including siRNA, CRISPR, lentiviral transduction or overexpression systems
• Ability to think and plan strategically as well as tactically
• Creativity and innovation in driving cutting-edge research with a strong publication record
• Ability to independently conduct a research project and effectively communicate the results
• Experience in data analysis
• Comfortable designing and executing independent experiments
• Demonstrated ability to analyze, interpret, and present complex biological datasets
• Strong scientific communication skills, including manuscript and presentation preparation
• Evidence of productivity through peer-reviewed publications and/or conference presentations
• Ability to work independently while collaborating effectively within multidisciplinary teams
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies
• Must be legally authorized to work in the United States without restriction
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older
• Previous research experience in chronic kidney disease, renal fibrosis, metabolic disease or tissue injury/repair biology
• Experience with Primary cell culture, Transwell permeable membrane culture systems
• RNA sequencing and transcriptomic data interpretation
• Bioinformatics analysis including differential expression, pathway enrichment and clustering approaches
• High-content imagers and image analysis tools

Responsibilities

• Design and conduct independent research project(s)
• Collaborate with other researchers within and outside Boehringer Ingelheim
• Effectively communicate and defend your own work in the context of team and department goals, both orally and in writing
• Establish an international reputation in your area of expertise with publications and conference participation at national and international events
• Publish first-author manuscript(s) and/or patenting of novel technologies/processes
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies

Skills

qPCR

Gene expression analysis

Protein assays

Fluorescence microscopy

Genetic perturbation

Data analysis

Education

Ph.D. in Biology or Pharmacology or related

Tools

Transwell permeable membrane systems

Fluorescence microscopy

Job description

The base salary for this position is $80,000.00 USD. The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please click here.

Compensation Data

The base salary for this position is $80,000.00 USD. The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please click here.

Description

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides an opportunity for all employees to collaborate internationally, offering visibility and the opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance.

Boehringer Ingelheim is seeking an enthusiastic, creative, and highly motivated Postdoctoral Fellow to join the Cardiometabolic Renal Disease Research (CRMDR) Department at our US headquarters in Ridgefield, CT. The Ridgefield campus, along with our sister sites in Texas and California, includes a thriving community of postdocs and PhD students that connects globally with their peers on our European campuses. The main responsibility of this position is to develop and validate translationally relevant human in vitro chronic kidney disease (CKD) models to uncover the cellular mechanisms and therapeutic opportunities underlying CKD progression.

As a Postdoctoral Fellow, you will be responsible for conducting independent research under the direct guidance of an experienced Principal Investigator and further supported by a team of experts committed to your success. You will interact with a diverse range of individuals (including mentors, fellow researchers, students, and collaborators from various institutions), and help to foster a collaborative research environment that facilitates exchange of knowledge and ideas. Your research will be focused on fundamental scientific questions and new methodologies that align with the goals of the department and contribute to Boehringer-Ingelheim’s innovative and growing pipeline. You will be expected to present your work to internal leadership and, ultimately, publish your findings in leading journals within the field. Postdoctoral Fellowships are three-year positions, with a potential one-year extension.

Duties & Responsibilities

With support from their advisor and team, the ideal candidate is expected to:

• Design and conduct their own independent research project(s)
• Collaborate with other researchers within and outside Boehringer Ingelheim
• Effectively communicate and defend their own work in the context of team and department goals, both orally and in writing
• Establish an international reputation in your area of expertise with publications and conference participation at national and international events
• Publish first-author manuscript(s) and/or patenting of novel technologies/processes
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies

Requirements

• Ph.D. degree in Biology, Pharmacology or related discipline, with a preference of no more than three (3) years of previous Post Doctoral experience
• Experience performing qPCR and gene expression analysis
• Experience with protein-based assays (western blotting, ELISA, MSD or similar)
• Experience with fluorescence microscopy and immunocytochemistry/immunofluorescence
• Experience with genetic perturbation approaches including siRNA, CRISPR, lentiviral transduction or overexpression systems
• Ability to think and plan strategically as well as tactically
• Creativity and innovation in driving cutting-edge research with a strong publication record
• Ability to independently conduct a research project and effectively communicate the results
• Experience in data analysis
• Comfortable designing and executing independent experiments
• Demonstrated ability to analyze, interpret, and present complex biological datasets
• Strong scientific communication skills, including manuscript and presentation preparation
• Evidence of productivity through peer-reviewed publications and/or conference presentations
• Ability to work independently while collaborating effectively within multidisciplinary teams
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies

Eligibility Requirements

• Must be legally authorized to work in the United States without restriction
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older

Desired Skills, Experience and Abilities

• Previous research experience in chronic kidney disease, renal fibrosis, metabolic disease or tissue injury/repair biology
• Experience with:
  • Primary cell culture (human primary cells preferred)
  • Transwell® permeable membrane culture systems
  • Co-culture or multicellular model systems
  • RNA sequencing and transcriptomic data interpretation
  • Bioinformatics analysis including differential expression, pathway enrichment and clustering approaches
  • High-content imagers and image analysis tools

Our Company

Boehringer Ingelheim is a biopharmaceutical company active in both human and animal health. As one of the industry's top investors in research and development, the company focuses on developing innovative therapies that can improve and extend lives in areas of high unmet medical need. Independent since its foundation in 1885, Boehringer takes a long-term perspective, embedding sustainability along the entire value chain. Our approximately 54,300 employees serve over 130 markets to build a healthier and more sustainable tomorrow. Learn more at www.boehringer-ingelheim.com.

Why Boehringer Ingelheim?

With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better.

Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent, authentic and bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed.

Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare. By being part of a team that is constantly innovating, you'll be helping to transform lives for generations.

Want to learn more? Visit https://www.boehringer-ingelheim.com