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Thomas-Jefferson-University-; Philadelphia (Philadelphia County); On-site; USD 120,000 - 160,000; Full time

Benefits offered by this job

Medical insurance

Tuition assistance

Retirement plans

Job summary

Thomas Jefferson University in Philadelphia seeks a highly motivated computational biologist to advance our RNA-related decoding projects. You will develop and implement bioinformatics tools and pipelines, and oversee the processing and analysis of next-generation sequencing data in a collaborative, multidisciplinary environment.

Applicants should hold a PhD in a relevant field, be fluent in R and Python, and have experience with RNA-Seq and Ribo-Seq data, visualization, and statistical

Qualifications

• PhD in Computational Biology, Bioinformatics, Computational Sciences, or related field.
• Proficiency in R and Python and Linux/Unix command line tools.
• Experience analyzing NGS data including RNA-Seq and Ribo-Seq; data evaluation and visualization.
• Basic knowledge of molecular biology techniques.
• Knowledge of statistical methods and their applications to biological datasets.
• Strong analytical, problem-solving, and collaboration skills in a multidisciplinary team.
• Publication track-record in relevant fields.

Responsibilities

• Develop and implement bioinformatics tools and pipelines.
• Oversee processing, management and analysis of NGS data.
• Support ongoing research projects.
• Collaborate with multidisciplinary team to translate data into insights.
• Contribute to manuscript preparation and data sharing.

Skills

Strong analytical and quantitative

Collaborative teamwork

Publication track-record

Education

PhD in Computational Biology or related field

Tools

R

Python

Linux/Unix

RNA-Seq

Ribo-Seq

Data visualization

Bioconductor

ENCODE

UCSC Genome Browser

Ensembl

NCBI databases

Illumina

Oxford Nanopore

Job description

Job DetailsA computational biologist position is immediately available in the laboratory of Dr. Fadia Ibrahim in the Department of Biochemistry and Molecular Biology, at Thomas Jefferson University. Our research program is focused on studying the molecular mechanism of a novel co-translational RNA decay process "ribothrypsis” and investigating the role of RNA dysregulation in neurodegenerative diseases. Our research integrates molecular biology, biochemistry, innovative RNA sequencing technologies, and advanced computational approaches. We are seeking a highly motivated computational biologist to support ongoing research projects, develop and implement bioinformatics tools and pipelines, and oversee the processing, management, and analysis of next generation sequencing (NGS) data.Job DescriptionRequired Qualifications:Ph.D. in Computational Biology, Bioinformatics, Computational Sciences, or a related discipline.Proficiency in R and Python and in working in Linux/Unix environments with commandline-based bioinformatics tools.Experience analyzing and interpreting NGS data, including RNA-Seq and Ribo-Seq, with expertise in data evaluation and visualization (e.g., differential expression, ribosome occupancy, poly(A) tail analysis, and modifications detection).Basic knowledge of molecular biology techniques and familiarity with biological data.Knowledge of statistical methods and their applications to biological datasets.Strong analytical, problem-solving, and quantitative skills, with the ability to collaborate effectively in a multidisciplinary team environment.• Publication track-record in relevant fields.Preferred Qualifications:Familiarity with NGS platforms, including Illumina and Oxford Nanopore Technologies.Demonstrated ability to integrate, mine, and analyze diverse large-scale biological datasets.Experience with commonly used bioinformatics resources, tools, and databases, including ENCODE, UCSC Genome Browser, Ensembl, Bioconductor, and NCBI databases.Experience managing computational servers and data storage and backup.Ability to formulate and develop scientific hypotheses that support ongoing research.Strong organizational, written, and verbal communication skills.Interested applicants are invited to submit a single PDF containing their CV, a cover letter outlining their research experience and interests, and the contact details of three referees.Work ShiftWorkday Day (United States of America)Worker Sub TypeRegularEmployee EntityThomas Jefferson UniversityPrimary Location Address1020 Locust Street, Philadelphia, Pennsylvania, United States of AmericaNationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University , home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health , nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region. Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years.Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.BenefitsJefferson offers a comprehensive package of benefits for full-time and part-time colleagues, including medical (including prescription), supplemental insurance, dental, vision, life and AD&D insurance, short- and long-term disability, flexible spending accounts, retirement plans, tuition assistance, as well as voluntary benefits, which provide colleagues with access to group rates on insurance and discounts. Colleagues have access to tuition discounts at Thomas Jefferson University after one year of full time service or two years of part time service. All colleagues, including those who work less than part-time (including per diem colleagues, adjunct faculty, and Jeff Temps ), have access to medical (including prescription) insurance.