Portfolio Operations Lead - Speed, Value & AI Delivery

Trimedx

Indianapolis (IN)

On-site

USD 110,000 - 160,000

Full time

14 days+
Application generator

Don’t send a generic resume — generate a resume and cover letter tailored to this exact role.

Get past ATS filters

Job summary

Trimedx seeks an experienced Senior Portfolio Operations Program Manager to lead portfolio health, drive speed-to-value, and coordinate product and IT teams for measurable ROI. The role emphasizes diagnostics, standardized practices, and organizational optimization in an AI-enabled landscape.

You will build dashboards, define KPIs, and report to executives, ensuring clear communication of risks and opportunities. A strategic leader with healthcare domain awareness will thrive here.

Qualifications

  • Minimum of seven or more years of program/portfolio management experience in product, IT operations, or technology delivery environments is required.
  • Experience building metrics, dashboards, and measurement frameworks, with strong data fluency.
  • Experience improving cross-team coordination, removing operational friction, and solving organizational challenges. Experience working in matrixed or distributed organization is preferred.
  • Ability to influence without authority; strong stakeholder management and communication skills. Comfortable working with ambiguity with a bias toward action.
  • Proven leader who understands technical products and services, including partnering with engineers to evaluate and make trade-offs.
  • End-to-end product development life-cycle experience, including commercialization planning, go-to market strategy, and the successful launch and adoption of new products and services.
  • Thorough understanding of development, engineering, and sales processes, including Agile/Scrum, SAFe, Pragmatic Marketing Framework, and Miller Heiman.
  • Experience in medical devices and/or the broader healthcare industry, including Clinical Engineering or Clinical Asset Management, is preferred.
  • Exceptional written and verbal communication skills, superior executive presentation skills, and sound judgment.
  • Strong strategic planning, organizational, and program management skills.

Responsibilities

  • Portfolio Strategy & Visibility: Own a single source of truth for portfolio health—initiatives, dependencies, blockers, and metrics. Analyze how work flows across product and IT; identify bottlenecks, redundancies, and misalignments. Conduct regular health reviews and elevate risks early, before they derail delivery.
  • Speed-to-Value Framework: Define what "speed" and "value" mean in your context. Build the measurement engine—dashboards, KPIs, and reporting cadences—that tracks cycle time, deployment frequency, time-to-first-value, and ROI. Ensure leadership uses this data for decision-making.
  • Root-Cause Problem-Solving: Lead diagnosis and resolution of high-impact organizational challenges (decision velocity, delivery delays, resource constraints, cross-team friction). Design systemic solutions, not band-aids. Measure outcomes and iterate.
  • Standardization & Operating Models: Develop playbooks, templates, and operating models that enable consistency without stifling innovation. Identify common pain points (vendor selection, onboarding, handoffs, approval workflows) and build scalable solutions. Drive adoption through partnership, not mandate.
  • Organizational Optimization: Recommend strategic changes to workflows, team structure, or capabilities based on data. Help eliminate bureaucracy while maintaining guardrails. Raise the bar for how we execute.
  • AI & Emerging Technology Adoption: Stay current with emerging tools and approaches (AI tooling, automation, modern delivery frameworks). Evaluate pragmatic adoption and help teams think about competitive advantages.
  • Stakeholder Leadership & Communication: Translate portfolio status and outcomes into executive briefs. Influence senior leadership on organizational priorities and trade-offs. Make progress visible; highlight wins and communicate risks clearly.
  • Relationship Building & Mentorship: Spend time with teams—understand their challenges, build trust, and be seen as a partner. Mentor Program Managers and Team Leads. Raise PM maturity across the organization.
  • All other duties as assigned.

Skills

Program/Portfolio management
Metrics & dashboards
Cross-team coordination
Stakeholder management
Technical product understanding
Agile/SAFe knowledge
Travel willingness

Education

Bachelor's Degree in Business, Management, Computer Science, or related discipline

Tools

SAFe Framework

Job description

Trimedx seeks an experienced Senior Portfolio Operations Program Manager to lead portfolio health, drive speed-to-value, and coordinate product and IT teams for measurable ROI. The role emphasizes diagnostics, standardized practices, and organizational optimization in an AI-enabled landscape.

You will build dashboards, define KPIs, and report to executives, ensuring clear communication of risks and opportunities. A strategic leader with healthcare domain awareness will thrive here.

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Senior Portfolio Operations Program Manager
Senior Portfolio Operations Program Manager

Trimedx • Indianapolis (IN)

On-site
USD 110,000 - 160,000
Senior Product & Portfolio Leader — AI-Driven Health Tech
Senior Product & Portfolio Leader — AI-Driven Health Tech

Optum • Eden Prairie (MN)

Remote
USD 159,000 - 273,000
Comprehensive benefits
Equity stock purchase
401k contribution
Senior Director, Product & Portfolio Strategy — Remote
Senior Director, Product & Portfolio Strategy — Remote

Optum • Eden Prairie (MN)

On-site
USD 159,000 - 273,000
AI-Driven Portfolio Operations Leader
AI-Driven Portfolio Operations Leader

Crossover • Cleveland (OH)

Hybrid
USD 4,500,000 - 5,500,000
Director, Specialty Product Portfolio & Agile Delivery
Director, Specialty Product Portfolio & Agile Delivery

McKesson Corporation • Columbus (OH)

On-site
USD 146,000 - 244,000
AI-Driven PMO Director for Healthcare & ROI
AI-Driven PMO Director for Healthcare & ROI

EMS Management & Consultants, Inc. • Clemmons (NC)

Hybrid
USD 95,000 - 105,000
Senior Clinical Engineering Site Leader
Senior Clinical Engineering Site Leader

Trimedx • Nashville (TN)

On-site
USD 160,000 - 230,000
Medical, dental, vision
401K
Paid time off
Senior Product Portfolio Operations Associate - Chief Analytics Office
Senior Product Portfolio Operations Associate - Chief Analytics Office

JPMorgan Chase & Co. • New York (NY)

On-site
USD 100,000 - 180,000
Portfolio Strategy & Analytics Leader
Portfolio Strategy & Analytics Leader

Scorpion Therapeutics • United States

On-site
USD 170,000 - 210,000
Clinical Portfolio Project Manager: Drive cross-functional delivery
Clinical Portfolio Project Manager: Drive cross-functional delivery

Syneos Health • Morrisville (NC)

Hybrid
USD 81,000 - 145,000
Car allowance
Health benefits
401k match
+3