Pilot-Scale Downstream Bioprocess Scientist

Lancesoft

Foster City (CA)

On-site

USD 55,000 - 83,000

Part time

4 days ago

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Job summary

Lancesoft is seeking a hands-on Downstream Bioprocess Associate to join our Biologics Pilot Lab in Foster City, CA on a 12-month contract. This 100% onsite role focuses on pilot-scale downstream purification in a fast-paced development environment.

You will plan and execute purification runs, operate AKTA systems, manage buffers, document results in SOPs and batch records, and support technology transfer from development to scale-up. Weekend coverage may be required.

Qualifications

Hands-on pilot-scale downstream bioprocess experience.
Experience with downstream purification operations such as chromatography, TFF, viral filtration, depth filtration, centrifugation, and buffer preparation.
Experience operating AKTA systems and working with UNICORN; chromatography column operation experience is strongly relevant.
Clear technical communication, documentation, organization, and collaborative problem-solving skills.
Your broader experience can come from bench, pilot, or manufacturing settings; hands-on pilot-scale work is the one must-have.
Nice to Have End-to-end purification process execution rather than experience with only one unit operation.
Biologics pilot plant, manufacturing support, technology transfer, or GMP-adjacent experience.
Experience with single-use facilities, controlled documentation, process scale-up, or comparability activities.
Flexibility to support occasional weekend or extended-hour run coverage.

Responsibilities

Plan and execute downstream purification runs, including clarification, chromatography, TFF, and viral filtration, in a schedule-driven pilot environment.
Prepare buffers and reagents;set up, operate, clean, and tear down pilot-scale and single-use equipment.
Pack and unpack chromatography columns, operate AKTA systems, and use UNICORN methods for run execution.
Document work in SOPs, batch records, run sheets, and summaries;capture observations and deviations clearly.
Monitor process performance, interpret data, troubleshoot during runs, and communicate findings to cross-functional partners.
Support process scale-up, comparability activities, technology transfer, lab readiness, and occasional weekend or extended-hour coverage.