Pharma Manufacturing Engineer: On-Site, Yield & Throughput

Penn Life Sciences; Pennsylvania; On-site; USD 85,000 - 110,000; Full time

Benefits offered by this job

401(k) company match

Paid Time Off

10 company holidays

Comprehensive medical/dental/vision/l—

Job summary

Penn Life Sciences is seeking a Manufacturing Engineer to directly support sterile pharmaceutical production on the manufacturing floor. The role focuses on improving process performance, equipment reliability, yield, and efficiency through hands-on troubleshooting and practical improvements.

Responsibilities include equipment inspections, root-cause analysis, implementing upgrades, maintaining AutoCAD drawings, and collaborating with Manufacturing, Maintenance, Quality, and Validation to

Qualifications

• 3+ years of directly relevant manufacturing experience.
• Experience in regulated environments (pharma/biotech/medical devices/food/chemical).
• Hands-on troubleshooting of manufacturing equipment and implementing improvements.
• Experience improving yield, throughput, downtime, scrap, cycle time, or other performance measures.
• Practical experience using AutoCAD to create and revise engineering drawings.
• Experience executing equipment modifications or manufacturing engineering projects.
• Bachelor's degree in a closely related engineering discipline.

Responsibilities

• Provide hands-on engineering support to manufacturing and packaging operations through equipment inspections, field observations, measurements, functional checks, testing, and mechanical troubleshooting.
• Investigate recurring equipment failures, line stoppages, process defects, and performance issues using production data, maintenance history, operator input, and structured root-cause analysis.
• Develop and implement equipment and process improvements that increase yield, throughput, equipment availability, and production efficiency while reducing scrap, rework, downtime, and variability.
• Evaluate cycle times, changeovers, equipment settings, material flow, and line performance to identify bottlenecks and capacity constraints and implement practical improvements.
• Apply continuous improvement methods to improve manufacturing processes, standardize effective operating practices, and verify that improvements deliver measurable, sustained results.
• Develop engineering solutions involving mechanical components, tooling, fixtures, equipment configurations, and process parameters in coordination with Manufacturing, Maintenance, Quality, and Validation.
• Create, interpret, field-verify, and revise AutoCAD drawings, including equipment and production layouts, mechanical details, P&IDs, and utility connections associated with manufacturing equipment. Maintain accurate redlines and final as-built documentation.
• Execute equipment upgrades and manufacturing improvement projects from scope development and technical evaluation through vendor coordination, installation, testing, startup, commissioning, qualification support, and operational turnover.
• Define and monitor performance measures, such as yield, downtime, cycle time, throughput, and overall equipment effectiveness (OEE), to prioritize opportunities and evaluate results.

Skills

Hands-on mechanical aptitude

AutoCAD proficiency

Process optimization

Data analysis

Root-cause analysis

Lean principles

cGMP awareness

Education

Bachelor's degree in Mechanical/Manufacturing/Industrial/Chemical/Electrical engineering

Tools

AutoCAD

Job description

Penn Life Sciences is seeking a Manufacturing Engineer to directly support sterile pharmaceutical production on the manufacturing floor. The role focuses on improving process performance, equipment reliability, yield, and efficiency through hands-on troubleshooting and practical improvements.

Responsibilities include equipment inspections, root-cause analysis, implementing upgrades, maintaining AutoCAD drawings, and collaborating with Manufacturing, Maintenance, Quality, and Validation to