Pediatric PBPK Modeling Intern (AI-Driven)

Merck

West Point (PA)

On-site

USD 39,000 - 111,000

Part time

3 days ago
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Job summary

Merck invites a highly motivated Intern to join the PDMB Translational Modeling Group to advance juvenile PBPK modeling and drug-development science. The 12-week internship will provide exposure to cutting-edge Model-Informed Drug Development (MIDD) approaches, safety assessment, and collaboration with TK and PBPK scientists.

The role includes building a foundational juvenile PBPK model, developing AI-enabled workflows, and delivering technical summaries and a final presentation during the

Qualifications

  • Currently pursuing Master's or Ph.D. in Pharmaceutical Sciences or related field.
  • Experience with PBPK or mechanistic modeling is required.
  • Ability to perform literature searches, extract quantitative parameters, summarize findings, and analyze data.

Responsibilities

  • Build juvenile PBPK model
  • Develop AI-enabled knowledge-generation workflows
  • Create resources supporting juvenile toxicity studies
  • Prepare technical summaries and progress presentations
  • Present outcomes at end-of-summer intern symposium

Skills

PBPK modeling
Mechanistic modeling
Systems pharmacology
Mathematical modeling
Literature search & data extraction
Full-time availability May/June 2027

Education

Master's or Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, Pharmacology, Toxicology, Biomedical Engineering, Systems Biology, Computational Biology, or related discipline

Tools

Simcyp
GastroPlus
PK-Sim
MATLAB
R

Job description

Merck invites a highly motivated Intern to join the PDMB Translational Modeling Group to advance juvenile PBPK modeling and drug-development science. The 12-week internship will provide exposure to cutting-edge Model-Informed Drug Development (MIDD) approaches, safety assessment, and collaboration with TK and PBPK scientists.

The role includes building a foundational juvenile PBPK model, developing AI-enabled workflows, and delivering technical summaries and a final presentation during the

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