Operational Technology Engineer (OTE)

Scorpion Therapeutics; Frederick (CO); On-site; USD 110,000 - 170,000; Full time

Job summary

Scorpion Therapeutics in Frederick, Colorado, seeks an Operational Technology Engineer to support GMP oligonucleotide manufacturing automation infrastructure. The role focuses on optimizing, securing, and maintaining compliant OT systems to enable reliable production.

You will manage OT infrastructure (SCADA, BAS, PLCs, data historians), advise on network resiliency, troubleshoot automation, ensure data integrity and cybersecurity, and support system validation, change controls, and GMP/FDA

Qualifications

• Bachelor's or master's degree required.
• Experience in automated manufacturing environments, GMP preferred.
• Knowledge of OT systems and regulatory standards.

Responsibilities

• Manage OT infrastructure (SCADA, BAS, PLCs, Data Historians).
• Advise on network and hardware resiliency best practices.
• Troubleshoot and maintain automation systems.
• Ensure data integrity and cybersecurity.

Skills

OT systems

SCADA

PLC

Cybersecurity

Data integrity

Regulatory compliance

Validation

Education

Bachelor's degree

Master's degree

Job description

Role: Operational Technology Engineer supporting GMP oligonucleotide manufacturing automation infrastructure.

Objectives: optimize and ensure reliable, secure, and compliant OT systems to support production.

Responsibilities

• manage OT infrastructure including SCADA, BAS, PLCs, Data Historians
• advise on best practices for network and hardware resiliency
• troubleshoot and maintain automation systems
• ensure data integrity and cybersecurity
• support system validation, change controls, and compliance with GMP and FDA guidelines
• collaborate with IT vendors and engineering teams

Requirements

• Bachelor's or master's degree
• 4+ years in automated manufacturing, preferably GMP
• strong knowledge of OT systems (SCADA, PLCs), cybersecurity, and regulatory standards
• experience in risk assessments and validation activities

Preferred

• GMP manufacturing experience, familiarity with data integrity and industry validation standards

High-value

• focus on GMP compliance, data integrity, cyber security, and automation systems within biopharma manufacturing

Work setup

• full-time, day shift, occasional travel