Operational Excellence Lead I (PharmD)

Openkrill; United States; Hybrid; USD 170,000 - 218,000; Full time

Benefits offered by this job

Health insurance

Dental insurance

Vision insurance

401k match

Paid time off

Annual incentive bonus

Job summary

Replimune is seeking an Operational Excellence Lead I (PharmD) to act as a field-based subject matter expert. You will partner with treatment centers to assess readiness, map workflows, and drive RP1 implementation with a focus on intratumoral RP1 handling and cold-chain logistics.

You will collaborate with medical, pharmacy, nursing, radiology, and practice leadership to develop scalable playbooks and tools, delivering consistent care improvements across sites while traveling extensively.

Qualifications

• PharmD degree required; BCOP certification is a plus.
• 5+ years of experience in biotechnology, pharmaceutical, healthcare operations, oncology, or clinical practice.
• 2+ years of clinical pharmacy experience in academic or community settings preferred.
• Experience launching oncology products in a specialty or hospital-based environment preferred.
• Experience in logistics/cold chain product handling and correct storage.
• Ability to travel extensively (50-75%).

Responsibilities

• Lead site readiness assessments and launch execution.
• Facilitate Operational Workflow Meetings with multidisciplinary teams.
• Develop best practices and workflow playbooks for RP1 implementation.
• Collaborate with care teams to operationalize RP1 and optimize workflows.
• Document site decisions, actions, and follow-up requirements.
• Travel across the United States to support site onboarding and execution.

Skills

Project management

Facilitation

Stakeholder engagement

Cross-functional collaboration

Communication

Multidisciplinary collaboration

Presentation skills

Education

PharmD degree

Bachelor's degree

BCOP certification

Tools

Inventory management systems

IRTs/IVRS/IXRS familiarity

Temperature monitoring systems

Job description

Overview

Replimune's mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient's lives depend on it.

At Replimune, we live by our values:

United: We Collaborate for a Common Goal.

Audacious: We Are Bold.

Dedicated: We Give Our Full Commitment.

Candid: We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

Position Summary

Replimune is seeking a highly motivated and proactive Operational Excellence Lead I (PharmD) to serve as a field-based subject matter expert responsible for supporting the successful integration of RP1 into treatment centers across the United States. Working as a member of the Operational Launch Excellence Team, this individual will work in close collaboration with field sales and other staff to partner with treatment centers to assess operational readiness, facilitate Operational Workflow Meetings, identify implementation barriers, and optimize workflows to ensure successful adoption of RP1.

The successful candidate will collaborate closely with multi-disciplinary care teams including but not limited to, medical oncology, pharmacy, nursing, interventional radiology, and practice leadership to help sites across the US operationalize RP1 and deliver positive treatment experiences. This individual will also contribute to the development of best practices, site readiness tools, and operational playbooks that can be scaled across the organization and adapted to future product launches.

This is a field-based position that involves a substantial travel commitment.

Key Responsibilities

1. Site Readiness & Launch Execution

• Conduct site readiness assessments for targeted treatment centers in area of professional expertise.
• Support implementation of the RP1 Site Readiness strategy.
• Partner with treatment centers to evaluate operational workflows, identify potential gaps, and develop action plans - with a particular emphasis in area of professional expertise.
• Ensure sites are prepared to successfully operationalize RP1 prior to first patient treatment.
• Assist sites in navigating the unique operational requirements associated with RP1, including product storage, thawing, scheduling, administration logistics, and multidisciplinary care coordination.

2. Operational Workflow Meetings

• Help facilitate Operational Workflow Meetings with Medical Oncologists, Surgical Oncologists, Interventional Radiologists, Oncology Nurses, Advanced Practice Providers, Pharmacists, Practice Administrators and the Scheduling and Operations Personnel- In particular, take a leading role in preparing and facilitating meetings and/or workstreams in area of professional expertise
• Conduct workflow mapping exercises to identify potential barriers and opportunities for optimization.
• Document site decisions, action items, and follow-up requirements.
• Provide recommendations based on established best practices and experience across treatment centers.
• Execute timely follow-up with sites to ensure implementation plans are progressing as intended.

3. Best Practice Development & Subject Matter Expertise

• Develop expertise in operationalizing RP1 as an intratumorally administered oncolytic viral therapy, especially in area of professional expertise.
• Become proficient in: - RP1 storage and handling requirements- Ultra-cold chain logistics- Product thawing and pharmacy workflows- Injection scheduling considerations- Live-virus biologic handling procedures- Interventional Radiology workflows- Multidisciplinary patient care coordination
• Capture operational learnings and insights from treatment centers.
• Identify emerging best practices and opportunities for process improvement.
• Contribute to the creation of workflow playbooks, readiness assessments, meeting materials, and implementation tools; take a lead role in area of professional expertise.
• Share learnings and best practices internally with Commercial, Medical Affairs, Training, and other functional teams.

Account Support & Relationship Management

• Establish credibility and trusted partnerships with treatment center stakeholders, especially in area of professional expertise.
• Support treatment centers throughout onboarding and early adoption phases.
• Monitor site progress and identify opportunities for workflow optimization.
• Promote consistency in implementation approaches across treatment centers with similar characteristics while adapting to site-specific constraints.

Qualifications Operational Excellence Lead I (PharmD)

Required

• Bachelor's Degree required, advanced PharmD degree or related studies preferred.
• Board Certified Oncology Pharmacist (BCOP) certification is a plus
• 5+ years of relevant experience in biotechnology, pharmaceutical, healthcare operations, oncology, specialty therapeutics, or clinical practice.
• 2+ years of experience in clinical pharmacy in an academic or community setting is strongly preferred.
• Experience launching oncology products in a specialty or hospital-based environment is strongly preferred.
• Experience in logistics/receipt of cold chain product, including but not limited to, confirmation of temperature monitoring data and correct storage of product in an institutional setting.
• Understanding of applicable regulatory guidelines and regulations and knowledge of IRT/IVRS/IXRS functions, or similar inventory management system.
• Demonstrated success working with multidisciplinary healthcare teams.
• Experience supporting oncology and/or specialty treatment centers.
• Strong understanding of healthcare operational workflows.
• Advanced facilitation, presentation, and stakeholder engagement skills; in particular, ability to facilitate workstream meetings related to area of professional expertise in an industry setting.
• Strong project management and problem-solving capabilities.
• Ability to travel extensively (50-75%).

Salary Range

Replimune is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $170,000 to $218,000. The exact base pay offered for this role will depend on various factors, including but not limited to the selected candidate’s unique set of qualifications, skills, and experience. Our current organizational needs also play a part in determining your final offer.

At Replimune, base pay is only one part of your total compensation package. The selected candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Replimune also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, flexible time off, and a number of paid holidays including year-end shutdown.

About Replimune

Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived a