Oligonucleotide Synthesis & Chemistry Co-op — Biotech Lab

Wave Life Sciences USA, Inc.; Lexington (MA); Vor Ort; USD 33.000 - 41.000; Vollzeit

Zusammenfassung

Wave Life Sciences in Lexington, Massachusetts, is seeking a highly motivated co-op student to join its Small Scale Synthesis, Oligonucleotide Synthesis and Chemistry teams. The position offers hands-on training in oligonucleotide synthesis, formulation, purification and analysis within a multidisciplinary biotech environment.

Completion of coursework in organic chemistry is required; biochemistry and analytical chemistry are a plus.

Qualifikationen

• Currently enrolled in an undergraduate science program in Chemistry, Biology, Biotechnology or related field.
• Coursework in organic chemistry is required; biochemistry and analytical chemistry are a plus.
• Understanding of laboratory best practices and safety protocols.
• Attention to detail and well organized.
• Laboratory experience with pipetting, weighing, and centrifugation preferred.
• Enthusiasm for DNA/RNA therapeutic development.

Aufgaben

• Prepare reagents and amidites for oligonucleotide synthesis.
• Learn about solid phase synthesis and operate a Mermade192X synthesizer.
• Purify oligonucleotides by preparative HPLC.
• Analyze oligonucleotides by LC-MS, UV and pH.
• Learn additional instrumentation including lyophilizers, speed vacs, nanodrop and UPLC.
• Gain exposure to the use of an automated liquid handler for high throughput plate-based sample preparation.
• Record and present data in an electronic laboratory notebook (ELN)

Kenntnisse

Undergraduate student

Organic chemistry coursework

Lab safety

Attention to detail

Pipetting

Weighing

Centrifugation

Teamwork

Organization

Ausbildung

Undergraduate science program

Tools

Mermade192X synthesizer

HPLC

LC-MS

UV

pH meter

Lyophilizers

Speed vac

Nanodrop

UPLC

ELN

Jobbeschreibung

Wave Life Sciences in Lexington, Massachusetts, is seeking a highly motivated co-op student to join its Small Scale Synthesis, Oligonucleotide Synthesis and Chemistry teams. The position offers hands-on training in oligonucleotide synthesis, formulation, purification and analysis within a multidisciplinary biotech environment.

Completion of coursework in organic chemistry is required; biochemistry and analytical chemistry are a plus.