Oligonucleotide Manufacturing Scientist I — Second Shift

Scorpion Therapeutics; Madison (WI); On-site; USD 60,000 - 70,000; Full time

Job summary

Scorpion Therapeutics, based in Madison, Wisconsin, is seeking an Associate Manufacturing Scientist I (second shift) to execute GMP-compliant manufacturing tasks and maintain accurate batch records. You will operate oligonucleotide manufacturing equipment, assist in synthesis/purification, perform LCMS analysis, and collaborate with Process Development, Analytical Development, QC, and QA to ensure quality and compliance.

Training and PPE are required, with a focus on safety and accuracy.

Qualifications

• 0-2 years of lab/manufacturing experience in biotech/pharma/chemical or related industries.
• Ability to follow detailed procedures and maintain accurate documentation.
• Strong attention to detail, quality focus, and communication skills.

Responsibilities

• Follow batch records, SOPs, and work instructions; document all operations in batch records and logbooks.
• Comply with GMP protocols.
• Operate large scale oligonucleotide manufacturing equipment (synthesizer, purification skid, TFF, lyophilizer, reactors, meters, pumps).
• Assist manufacturing chemists during synthesis and purification (reagent prep, mobile phase prep, column packing, fraction collection).
• Perform oligonucleotide/intermediate analysis via LCMS.
• Communicate with cross-functional groups (Process Development, Analytical Development, Quality Control, Quality Assurance).
• Maintain a clean workspace; ensure safety with required PPE.
• Track and update raw material usage in D365 ERP; act as production campaign lead; assist with new personnel training.

Skills

0-2 years lab/manufacturing experience

Follow detailed procedures

Attention to detail & communication

Independent work in fast-paced env

Education

Bachelor's degree in Chemistry, Biochemistry, Biology, Chemical Engineering, or related field

Tools

LC-MS instrumentation

Chromatography/Filtration/Purification

ERP familiarity (D365)

Job description

Scorpion Therapeutics, based in Madison, Wisconsin, is seeking an Associate Manufacturing Scientist I (second shift) to execute GMP-compliant manufacturing tasks and maintain accurate batch records. You will operate oligonucleotide manufacturing equipment, assist in synthesis/purification, perform LCMS analysis, and collaborate with Process Development, Analytical Development, QC, and QA to ensure quality and compliance.

Training and PPE are required, with a focus on safety and accuracy.