NPI Scientist: Scale-Up & Tech Transfer for Antibodies

Nautilus Biotechnology

San Carlos (CA)

On-site

USD 120,000 - 180,000

Full time

14 days+

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Job summary

Nautilus seeks a Scientist or Senior NPI Scientist to bridge R&D and manufacturing. You will develop and refine methods for production and testing of antibodies and related reagents, contribute to scale-up, tech transfer, and process validation in a fast-moving setting.

Responsibilities include drafting SOPs and specs, investigating issues, and partnering with R&D to establish QC release criteria. The role is based in San Carlos, CA, full-time onsite, requiring hands-on laboratory work and

Qualifications

PhD in chemistry, biochemistry, molecular biology or related field with 2–3 years of industry experience; or MS with 3-5 years, or BS with 5-7+ years of relevant industry experience.
Deep knowledge of protein biochemistry, protein purification, reagent formulation or analytical chemistry.
Experience in BOM setup using Arena/Agile software, costing analysis, supply chain set-up, vendor management.
Hands‑on experience working in controlled development or manufacturing environment (ISO9001 & ISO 13485).
Strong interpersonal and communication skills, with the ability to document processes clearly and help train others to execute SOPs.
Proficiency in Excel; familiarity with project tracking tools (Smartsheet, Microsoft Project, or similar).
Willingness to work hands‑on in the lab and production environment.
Demonstrate project management skills with an ability to meet project timelines and deliverables.

Responsibilities

Own the transfer of newly developed biochemical reagents, proteins, antibodies and sequencing assays from R&D phase to commercial.
Design, develop and optimize scale-up studies, improve yield, stability and robustness of complex formulations and processes.
Author documents including SOPs, batch records, and technical reports, while ensuring compliance with quality standard.
Conduct root-cause analysis and provide technical support to resolve production-line anomalies during pilot and production phases.
Partnering with the R&D to help establish QC release criteria and specifications for all manufactured reagents.
Performing hands‑on laboratory and production work, including reagent formulation, conjugation, and analytical sample preparation.