Neuroscience In Vivo Pharmacology Scientist

Atalanta Therapeutics; Boston (MA); On-site; USD 100,000 - 155,000; Full time

Job summary

Atalanta Therapeutics seeks an Associate Scientist/Senior Associate Scientist to join the in vivo pharmacology group in Boston. The role focuses on survival surgeries, CNS tissue processing, and pharmacodynamic assessments of oligonucleotides in preclinical studies.

You will perform dosing via brain injections, intrathecal routes, and systemic administration, and lead tissue analysis to support multiple drug discovery programs. Collaboration and rigorous data documentation are essential.

Qualifications

• Bachelor’s or Master’s degree with 6+ years of industry/academic experience.
• Hands-on in vivo studies including rodent stereotactic and intrathecal surgeries.
• Experience with CNS tissue collection and molecular analyses (qRT-PCR, ELISA, IHC).
• Excellent interpersonal, organizational, and data‑presentation skills.

Responsibilities

• Design and execute assays to assess pharmacological activity, biodistribution and efficacy of oligonucleotides.
• Perform dosing via brain injections, intrathecal and systemic routes including HDI and IV/IP/SC/IM.
• Perfuse rodents and collect tissues for CNS studies.
• Conduct molecular/biochemical assays and analyze target mRNA/protein levels.
• Manage tissue analysis and coordinate sample transfer from external facilities.
• Analyze data independently and present results to the team.

Skills

In vivo pharmacology

Rodent surgeries

Pharmacology dosing

Molecular assays

Tissue processing

Data analysis

Communication

Education

Bachelor’s degree

Master’s degree

Job description

Atalanta Therapeutics seeks an Associate Scientist/Senior Associate Scientist to join the in vivo pharmacology group in Boston. The role focuses on survival surgeries, CNS tissue processing, and pharmacodynamic assessments of oligonucleotides in preclinical studies.

You will perform dosing via brain injections, intrathecal routes, and systemic administration, and lead tissue analysis to support multiple drug discovery programs. Collaboration and rigorous data documentation are essential.