mRNA Process Development Scientist

Eurofins PSS Insourcing Solutions; Boston (MA); On-site; USD 44,000 - 56,000; Full time

Job summary

Eurofins PSS Insourcing Solutions is seeking a process development scientist to join the mRNA process development team in Boston. The role focuses on early and operational tech development, producing and analyzing RNA constructs and carrying out preparative and purification chromatography.

The successful candidate will perform IVT and purification experiments, analyze data, and maintain rigorous documentation in a collaborative, safety-focused environment.

Qualifications

• B.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with 1+ years of relevant laboratory experience, or M.S. with at least 6 months of relevant laboratory experience.
• Experience with molecular biology and RNA biochemistry methods including IVT.
• Experience with tangential flow filtration, capillary gel electrophoresis, Akta chromatography, HPLC, and ELISA.
• Experience with good documentation practices and electronic lab notebooks such as Benchling.
• Strong commitment to safety protocols and procedures.
• Excellent communication, time-management, and problem-solving skills.
• Ability to work independently and in a team; adaptable in a fast-paced environment.
• Authorization to work in the United States indefinitely without sponsorship.

Responsibilities

• Perform in vitro transcription (IVT) and purification experiments (chromatography, TFF).
• Conduct analytical methods including CGE, Akta chromatography, HPLC, and ELISA.
• Process data and provide summaries to team members and stakeholders.
• Prepare buffers, reagents, and stock solutions per SOPs.
• Maintain updated lab notebooks and manage materials/equipment; assist troubleshooting.
• Uphold high lab safety standards.

Skills

Molecular biology

RNA biochemistry

Attention to detail

Data analysis

Written & verbal communication

SOPs adherence

Education

B.S./M.S. in chemistry/biochemistry/related

Tools

Benchling

IVT

CGE

HPLC

AKTA chromatography

Tangential Flow Filtration

Job description

The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

Job Description

We are seeking a process development scientist to join the messenger-RNA (mRNA) process development team. The successful candidate will be contributing to early and operational tech development. In this role, the successful candidate will be responsible for production and analysis of RNA constructs and carrying out preparative and purification chromatography.

• Perform in vitro transcription (IVT) and purification (chromatography, tangential flow filtration) experiments.
• Perform analytical methods including but not limited to capillary gel electrophoresis (CGE), Akta chromatography, HPLC, and ELISA.
• Process the data and provide data summaries to team members and key stakeholders.
• Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes and SOPs.
• Maintain an updated lab notebook, order materials, maintain lab equipment, and support equipment troubleshooting as needed.
• Uphold lab safety to the highest level of standards.

Qualifications

Basic Minimum Qualifications:

• B.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with 1+ years of relevant laboratory experience, or M.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with at least 6 months of relevant laboratory experience.
• Experience with molecular biology and RNA biochemistry methods including IVT
• Experience with tangential flow filtration (TFF), capillary gel electrophoresis (CGE), Akta chromatography, HPLC, and ELISA.
• Experience with good documentation practices and electronic lab notebooks such as Benchling.
• Unwavering commitment to safety protocols and procedures.
• Strong attention to detail, organizational, and time-management skills.
• Excellent written and verbal communication, work planning, data analysis, problem-solving, and critical thinking skills.
• Ability to learn new techniques, perform multiple tasks simultaneously, follow SOPs, and comply with company policies.
• Ability to work independently and as part of a team, inquisitive, self-motivated, and enthusiasm to learn and contribute in a fast-paced environment.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Preferred Qualifications

• Experience developing processes for RNA-LNP, protein, mAB, or AAV therapeutics or vaccines (experience with RNA therapeutics is preferred).

Additional Information

Position is Full Time, Monday-Friday, 8am-5pm. Candidates currently living within a commutable distance of Boston, MA are encouraged to apply.

Excellent full-time benefits include:

• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Eligibility for yearly goal-based bonus & merit-based increases
• Compensation: $32.00-$41.00 per hour based on education and related experience

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.