mRNA Analysis & Characterization Scientist

BioSpace; Waltham (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Sanofi Pasteur is seeking an mRNA Analytical Development Scientist to strengthen the Analytical Sciences group in R&D. The role focuses on developing and validating robust LC-MS based methods for mRNA vaccine characterization, supporting release and stability testing, and collaborating with CMC teams.

The candidate should have PhD or MSc with pharma/biotech analytical experience and a track record in method development and complex experiments, with strong writing skills for regulatory filings.

Qualifications

• PhD or MSc with pharma/biotech analytical experience.
• Experience in characterizing proteins, oligonucleotides, lipids and degradants via LC-MS.
• Ability to develop and improve complex analytical methods.

Responsibilities

• Develop advanced biochemical and biophysical assays, focusing on LC-MS characterization for mRNA vaccine process.
• Collaborate with analytical leads to support CMC activities.
• Write and review method documentation and characterization reports for regulatory filings.
• Design and execute complex experiments independently, and report results.
• Support QC and CRO investigations, deviations, and change control.
• Train junior team members and promote lab safety and quality compliance.

Skills

LC-MS characterization

Analytical method development

Biochemical & biophysical assays

Team collaboration

Education

PhD in Analytical Chemistry / Biochemistry / Biotechnology

MSc in Analytical Chemistry / Biochemistry / Biotechnology

Tools

LC-MS instruments

Job description

Sanofi Pasteur is seeking an mRNA Analytical Development Scientist to strengthen the Analytical Sciences group in R&D. The role focuses on developing and validating robust LC-MS based methods for mRNA vaccine characterization, supporting release and stability testing, and collaborating with CMC teams.

The candidate should have PhD or MSc with pharma/biotech analytical experience and a track record in method development and complex experiments, with strong writing skills for regulatory filings.