ML Scientist: Protein Design & Pretraining

Profluent Bio; Emeryville (CA); On-site; USD 200,000 - 330,000; Full time

Benefits offered by this job

Equity participation

401(k) with employer match

Health/dental/vision insurance

Generous PTO

Job summary

Profluent Bio in Emeryville, CA is seeking a motivated ML Scientist to lead research on pretraining large-scale models for biomolecular design. You will prototype and evaluate new models in a fast-paced, cross-disciplinary environment with biologists and engineers.

As an early employee, you will shape the direction of our ML efforts, collaborate across teams, and help build the infrastructure and datasets needed to advance protein language modeling.

Qualifications

• PhD (or equivalent) in a related field.
• Experience designing and evaluating novel ML models for biomolecular design.
• Publications at major ML conferences (NeurIPS, ICML, ICLR) or Nature/Science/Nature Biotech/Nature Methods/PNAS or experience pre-training LLMs at frontier labs.
• Experience with PyTorch or Jax.

Responsibilities

• Design and develop state-of-the-art autoregressive, diffusion and representation learning models for protein design.
• Collaborate across the machine learning and protein design teams to apply, adapt and improve pretraining techniques from other domains to biomolecular deep learning models.
• Architect, implement, and optimize core infrastructure to support the pretraining of protein language models.
• Curate relevant datasets and design tasks for rigorous evaluation of generative models.
• Implement, analyze, and interpret multiple computational approaches and present results to colleagues in regular update meetings.
• Work within a collaborative, fast-paced, interdisciplinary team across biology and machine learning to help shape the scientific and strategic vision of the company.

Skills

Self-directed researcher

Protein design awareness

Pretraining large models

Education

PhD (or equivalent) in relevant field

Tools

PyTorch

Jax

Job description

Profluent Bio in Emeryville, CA is seeking a motivated ML Scientist to lead research on pretraining large-scale models for biomolecular design. You will prototype and evaluate new models in a fast-paced, cross-disciplinary environment with biologists and engineers.

As an early employee, you will shape the direction of our ML efforts, collaborate across teams, and help build the infrastructure and datasets needed to advance protein language modeling.