Mid-Level Research Lab Specialist: Genomics & Neuro-Oncology

University of Michigan; Ann Arbor (MI); Hybrid; USD 60,000 - 85,000; Full time

Benefits offered by this job

Hybrid work options

Job summary

The Misek laboratory at Chad Carr Pediatric Brain Tumor Center, Department of Pediatrics, University of Michigan, seeks a Research Lab Specialist Intermediate to drive cancer genomics research and lab operations. The role blends hands-on experiments (75%) with lab management (25%), collaborating with a PI and supporting personnel.

Responsibilities include establishing workflows, performing CRISPR screens, NGS work, cloning, and data presentation; mentoring undergrads, ensuring safety, and

Qualifications

• Bachelor’s degree in biological sciences or equivalent education/experience.
• 4–5 years of related experience in a biomedical research setting.
• Three years of hands-on wet-lab experience beyond undergraduate degree; graduate study may count.
• Hands-on mammalian tissue culture in a BSL-2 environment; core molecular techniques (nucleic acid extraction, PCR/qPCR, cloning, immunoblotting).
• Experience with or interest in NGS library preparation; strong organizational skills and meticulous record keeping.
• Ability to work independently, manage multiple projects, and communicate results effectively.

Responsibilities

• Independently perform experiments to support cancer genomics and pediatric neuro-oncology research.
• Establish NGS sample prep workflows and conduct molecular biology experiments.
• Assist in writing manuscripts and grants; maintain and develop genetically engineered cancer models.
• Design, execute, troubleshoot CRISPR screens and related sequencing workflows.
• Supervise undergraduate staff and contribute to lab operations and safety.Recordkeeping and protocol maintenance.

Skills

Mammalian cell culture

PCR/qPCR

Cloning

Immunoblotting

NGS library prep

CRISPR/Cas9

Data presentation

Education

Bachelor's degree in biological sciences

Advanced degree (MS or equivalent)

Job description

The Misek laboratory at Chad Carr Pediatric Brain Tumor Center, Department of Pediatrics, University of Michigan, seeks a Research Lab Specialist Intermediate to drive cancer genomics research and lab operations. The role blends hands-on experiments (75%) with lab management (25%), collaborating with a PI and supporting personnel.

Responsibilities include establishing workflows, performing CRISPR screens, NGS work, cloning, and data presentation; mentoring undergrads, ensuring safety, and