Microfluidics / Consumable Engineer

System One; Boston (MA); On-site; USD 86,000 - 123,000; Full time

Job summary

System One is seeking a Microfluidics/Consumable Engineer in Boston, MA for a contract-to-hire onsite role. You will own the engineering of the consumables for the manufacturing platform and manage the end-to-end flow path across DNA template preparation, purification, and encapsulation.

You should have MS/PhD in engineering with microfluidics, 6+ years of hands-on experience, and expertise in low-Reynolds-number flow, materials selection, and fabrication methods.

Qualifications

• MS or PhD in mechanical, chemical, or biomedical engineering, or a related discipline with a microfluidics specialization.
• At least six years of experience designing and building microfluidic or milli-fluidic devices that have gone into real use.
• Strong understanding of low-Reynolds-number flow, mixing, pressure drop, residence time, and microfluidic nanoparticle formation, including how mixing parameters impact particle size, polydispersity, and encapsulation efficiency.
• Hands-on fabrication experience across at least two of the following: injection molding, hot embossing, laser micromachining, CNC micro-milling, film lamination, laser or ultrasonic welding, and pressure-sensitive adhesive bonding.
• Experience in fluidic network design and/or CFD applied to real design decisions.

Responsibilities

• Own the engineering of the consumables for the manufacturing platform.
• Manage the flow path carrying every unit operation of the end-to-end process including DNA template preparation/amplification, purification/filtration, and encapsulation.
• Design channel geometry and hydrodynamics, mixing elements, valve and actuator placement, in-line sensing locations, and fluid-path interfaces to various subsystems.
• Select materials and joining methods compatible with sterilization under ISO 11137.
• Conduct bench de-risking of cartridge unit operations, fabricate the initial cartridge lot, and verify cartridges against set acceptance criteria.

Skills

Microfluidics design

CFD

Prototyping

Materials selection

Education

MS/PhD in mechanical/chemical/biomedical engineering with microfluidics

Tools

Injection molding

Laser micromachining

Job description

Job Title: Microfluidics / Consumable Engineer

Location: Boston, MA

Type: Contract to Hire

Compensation: $75.96

Work Model: Onsite – onsite

Hours: Standard business hours

Security Clearance: Not specified

Overview

Join a growing biotechnology organization in the U.S. that focuses on next-generation RNA medicine manufacturing. The Microfluidics/Consumable Engineer will be responsible for the engineering of the consumables for the manufacturing platform.

Responsibilities

• Own the engineering of the consumables for the manufacturing platform.

• Manage the flow path carrying every unit operation of the end-to-end process including DNA template preparation/amplification, purification/filtration, and encapsulation.

• Design channel geometry and hydrodynamics, mixing elements, valve and actuator placement, in-line sensing locations, and fluid-path interfaces to various subsystems.

• Select materials and joining methods compatible with sterilization under ISO 11137.

• Conduct bench de-risking of cartridge unit operations, fabricate the initial cartridge lot, and verify cartridges against set acceptance criteria.

Requirements

• MS or PhD in mechanical, chemical, or biomedical engineering, or a related discipline with a microfluidics specialization.

• At least six years of experience designing and building microfluidic or milli-fluidic devices that have gone into real use.

• Strong understanding of low-Reynolds-number flow, mixing, pressure drop, residence time, and microfluidic nanoparticle formation, including how mixing parameters impact particle size, polydispersity, and encapsulation efficiency.

• Hands-on fabrication experience across at least two of the following: injection molding, hot embossing, laser micromachining, CNC micro-milling, film lamination, laser or ultrasonic welding, and pressure-sensitive adhesive bonding.

• Experience in fluidic network design and/or CFD applied to real design decisions.

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

#M3

#LI-KM2

Ref: #558-Scientific

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.