Method Development Chemist

Actalent; Barrington (IL); On-site; USD 47,000 - 59,000; Full time

Benefits offered by this job

Medical, dental & vision

401(k) Retirement Plan

Life Insurance

Job summary

Actalent is seeking a Method Development Chemist in Barrington, IL to develop and validate analytical methods for biologics and complex chemistries. The role requires hands-on HPLC experience, data interpretation, and technical leadership to ensure compliant results within turnaround targets.

You will write SOPs, mentor analysts, and lead investigations while advancing method transfer and instrument setup. This onsite, contract-to-hire position offers competitive hourly pay and benefits.

Qualifications

• BA/BS degree in chemistry or a related science field.
• 3–5 years of experience in analytical chemistry, preferably with hands-on HPLC and method development.
• Proven experience in analytical method development and validation, ideally for biologic drugs.
• Strong experience in peptide chemistry, biomolecules, enzymes, and antibody drug conjugates.
• Demonstrated ability to perform routine and specialized analytical testing in a laboratory environment.

Responsibilities

• Develop and validate analytical methods for biologic drugs and conjugates.
• Perform routine and non-routine analyses using appropriate instrumentation.
• Guide analysts on analytical methods and instrumentation questions.
• Review, interpret, and approve analytical data independently.
• Write and maintain SOPs and STPs.
• Enter data into lab systems and maintain records.
• Identify and resolve instrument and analytical problems.
• Lead QA investigations and support corrective actions.
• Work independently on complex analytical challenges.
• Set up new instrumentation and method transfers.
• Oversee operation of lab equipment and maintenance.
• Stay current with new analytical methods relevant to biology and chemistry.
• Perform statistical analyses on QC samples to ensure specifications.

Skills

Analytical chemistry

HPLC

Method development

Data analysis

Documentation

Education

BA/BS in Chemistry

Tools

HPLC systems

Job description

Job Title: Method Development Chemist

Job Description

The Method Development Chemist develops, validates, and implements analytical methods for complex chemical and biologic compounds, with a focus on biologic drugs such as peptides, biomolecules, enzymes, and antibody drug conjugates. This role combines hands‑on laboratory analysis, advanced data interpretation, and technical leadership to ensure high-quality, compliant results that meet laboratory benchmarks and turnaround time expectations.

Responsibilities

• Develop and validate analytical methods for biologic drugs, including peptides, biomolecules, enzymes, and antibody drug conjugates, as well as traditional chemical compounds.
• Perform routine and non‑routine analysis in analytical laboratory departments using appropriate instrumentation and methodologies.
• Provide guidance and troubleshooting support to routine analysts on analytical methods, instrumentation issues, and methodology questions.
• Review, interpret, and approve analytical data independently, ensuring accuracy, reliability, and compliance with laboratory standards.
• Write, review, and maintain Standard Operating Procedures (SOPs) and Standard Test Procedures (STPs) to support analytical activities.
• Enter data accurately into laboratory systems and documentation tools, maintaining clear and complete records.
• Identify, investigate, and resolve instrument and analytical problems, recommending and implementing process improvements.
• Lead or conduct quality assurance (QA) investigations independently, documenting findings and supporting corrective and preventive actions.
• Work independently on complex analytical challenges, providing insight and recommendations for problem solving and method optimization.
• Set up new instrumentation and procedures for specialized or non‑routine analyses, including method transfer and implementation.
• Oversee the operation of laboratory equipment, including monitoring supply levels, coordinating repairs, and ensuring instruments remain in good working condition.
• Stay current with new and emerging analytical methods, technologies, and best practices relevant to biologic and chemical analysis.
• Perform statistical analyses on quality control samples to confirm compliance with established specifications and quality standards.
• Ensure the quality and quantity of work consistently meets established laboratory benchmarks and performance metrics.
• Follow all safety requirements in the laboratory, including appropriate use of safety glasses, gloves, lab coats, and other protective equipment.
• Ensure IDC sample requirements and other internal sample handling standards are met in a timely and compliant manner.
• Adhere to all company procedures, policies, and regulatory guidelines in daily laboratory operations.
• Participate in ongoing laboratory skills inventory and training activities to maintain and enhance technical competencies.
• Manage workload to achieve required turnaround times for analyses and reports while maintaining high quality standards.
• Collaborate effectively with colleagues across the laboratory, sharing knowledge and supporting a team‑oriented environment.

Qualifications

• BA/BS degree in chemistry or a related science field.
• 3–5 years of experience in analytical chemistry, preferably with hands‑on HPLC and method development.
• Proven experience in analytical method development and validation, ideally for biologic drugs rather than only small‑molecule pharmaceuticals.
• Strong experience in peptide chemistry, biomolecules, enzymes, and antibody drug conjugates.
• Demonstrated ability to perform routine and specialized analytical testing in a laboratory environment.
• Strong analytical and problem‑solving skills, with the ability to interpret complex data independently.
• Ability to interact effectively with staff at all levels and communicate technical information clearly.
• Effective time management and organizational skills, with the ability to handle multiple projects simultaneously.
• Strong verbal and written communication skills for documentation, reporting, and SOP/STP preparation.
• Ability to work both independently and collaboratively in a team environment.
• Capability to make sound decisions quickly and effectively in a fast‑paced laboratory setting.
• Proficiency with Microsoft Office applications for data handling, reporting, and documentation.

Job Type & Location

This is a Contract to Hire position based out of Barrington, IL.

Pay and Benefits

The pay range for this position is $33.65 - $43.27/hr.

Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job‑related factors.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre‑tax and Roth post‑tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long‑term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Barrington,IL.

Application Deadline

This position is anticipated to close on Sep 24, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email [e-mail] for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.