Membrane Protein Research Specialist - Expression & Purification

University of Minnesota; Austin (MN); On-site; USD 44,000 - 55,000; Full time

Job summary

The Hormel Institute at the University of Minnesota in Austin, MN seeks a research professional to support its membrane-protein program, focusing on mammalian cell culture, recombinant protein production and purification, and biochemical characterization. Responsibilities include experimental planning, data analysis, training of laboratory personnel, and maintaining standardized procedures on-site.

This 100% appointment Civil‑Service position offers competitive pay and benefits within the

Qualifications

• BA/BS degree plus at least four years of relevant experience, or a combination of education and relevant work experience to equal at least eight years.
• Experience independently planning and executing laboratory experiments.
• Experience optimizing experimental procedures and troubleshooting nonroutine research problems.
• Experience analyzing and interpreting experimental data.
• Ability to train or provide technical guidance to other laboratory personnel.

Responsibilities

• Plan and optimize mammalian expression experiments.
• Develop and evaluate transient and stable expression conditions.
• Troubleshoot nonroutine cell-culture and protein-expression problems.
• Establish reproducible production workflows and train laboratory personnel in mammalian cell-culture and expression methods.
• Design and optimize purification strategies for membrane-protein targets and complexes.
• Systematically troubleshoot protein extraction, purification, stability, and reconstitution problems.
• Optimize biochemical and functional assays and interpret experimental results.
• Develop reproducible purification and characterization workflows and train other laboratory personnel in their use.
• Plan experiments addressing defined research questions.
• Select appropriate experimental conditions and controls.
• Analyze and interpret biochemical, biophysical, and structural data relevant to assigned projects.
• Use experimental results to propose and execute follow-up experiments.
• Contribute to preparation of figures, methods, and research materials for presentations and publications.
• Develop and maintain standardized laboratory procedures and documentation.
• Train laboratory personnel in specialized experimental workflows.
• Identify operational problems affecting experimental reproducibility or efficiency and implement solutions.
• Coordinate use and maintenance of research equipment relevant to assigned workflows.
• Perform other research-related duties necessary to support the scientific objectives of the laboratory.

Skills

Experiment planning

Independent execution

Troubleshooting

Data interpretation

Train others

Education

BA/BS + 4 years exp

Job description

The Hormel Institute at the University of Minnesota in Austin, MN seeks a research professional to support its membrane-protein program, focusing on mammalian cell culture, recombinant protein production and purification, and biochemical characterization. Responsibilities include experimental planning, data analysis, training of laboratory personnel, and maintaining standardized procedures on-site.

This 100% appointment Civil‑Service position offers competitive pay and benefits within the