Medicinal Chemist, Synthesis Technologies

Novartis; Cambridge (MA); On-site; USD 81,000 - 151,000; Full time

Job summary

Novartis in Cambridge, MA is seeking a Research Scientist II to join the Synthesis Technologies Team within Global Discovery Chemistry. You will conduct synthesis and purification from milligram to multi-gram scale, collaborate with global teams, and contribute to the discovery of transformative medicines.

The role requires a BS or MS in synthetic organic chemistry with 2–5 years of postgrad experience, strong data management, and a mindset toward green synthesis practices.

Qualifications

• BS or MS in synthetic organic chemistry with 2–5 years of postgraduate experience.
• Experience in multi-step preparation of drug substances.
• Strong observational, organizational, and data management skills.
• Interest in green and sustainable synthesis methods.
• Excellent communication to collaborate with medicinal chemistry teams.

Responsibilities

• Independently conduct task-oriented synthesis and purification from milligram to multi-gram scale.
• Anticipate pitfalls and optimize routes/conditions.
• Develop and deploy cutting-edge synthetic methods for building blocks and drug substances.
• Collaborate with internal and external chemistry teams.
• Perform structural and stereochemical elucidation.
• Adhere to laboratory safety policies.

Skills

Synthetic organic chemistry

Drug substance synthesis

Synthesis planning

Data/documentation

Green chemistry

Education

BS/MS in synthetic organic chemistry

Job description

Novartis in Cambridge, MA is seeking a Research Scientist II to join the Synthesis Technologies Team within Global Discovery Chemistry. You will conduct synthesis and purification from milligram to multi-gram scale, collaborate with global teams, and contribute to the discovery of transformative medicines.

The role requires a BS or MS in synthetic organic chemistry with 2–5 years of postgrad experience, strong data management, and a mindset toward green synthesis practices.