Medical Director, Clinical Development, Genetics Medicine

Regeneron Pharmaceuticals, Inc.; Tarrytown (GA); On-site; USD 285,000 - 386,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. seeks a Medical Director, Clinical Development to lead cross-functional study teams and shape the clinical development strategy for genetic medicines from First in Human through Phase 3.

This on-site role in Tarrytown, NY involves collaboration with discovery scientists, translational researchers, and regulatory colleagues. The position requires an MD (MD/PhD or related research experience preferred), board certification/eligibility in hepatology,

Qualifications

• MD degree required; MD/PhD or research experience preferred.
• Board certification/eligibility in hepatology, gastroenterology, endocrinology, or nephrology preferred.
• 2–3+ years of clinical practice or industry experience preferred.
• Track record of success in clinical or scientific research settings.

Responsibilities

• Lead cross-functional teams to craft clinical development strategy for genetic medicines.
• Partner with discovery and translational scientists to understand targets across MASH, metabolism, rare diseases, and other therapeutic areas.
• Author and finalize protocols, amendments, monitoring plans, SAPs, and regulatory submissions.
• Evaluate the benefits and risks of assigned therapeutic candidates to inform program decisions.
• Oversee trial execution, including adverse event review and ongoing monitoring of patient health and data quality.
• Ensure team compliance with FDA, EMA, ICH, and GCP guidelines.
• Conduct literature reviews to identify development opportunities from mechanistic, pharmacological, and clinical perspectives.
• Represent clinical science in communications and meetings with regulatory agencies.

Skills

Clinical trial leadership

Cross-functional collaboration

Regulatory submissions

Literature review

Strategic thinking

Education

MD degree

Board Certification/Eligibility

Job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Medical Director, Clinical Development to join our MASH/Metabolism team, supporting genetic medicine programs from First in Human through Phase 3. In this role, you will lead cross-functional study teams to shape clinical development strategy and ensure the scientific integrity of trials, while collaborating closely with discovery scientists, translational researchers, and regulatory colleagues.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Tarrytown, NY


• Work model/flexibility: On-site four days per week


• Travel percentage: 10% to relevant conferences/congresses

Discover your role:

• Lead cross-functional teams to craft novel clinical development strategy for genetic medicines


• Partner with discovery and translational scientists to understand emerging genetic targets across MASH, metabolism, rare diseases, and other therapeutic areas


• Author and finalize protocols, amendments, monitoring plans, SAPs, and regulatory submissions


• Evaluate the benefits and risks of assigned therapeutic candidates to inform program decisions


• Oversee trial execution, including adverse event review and ongoing monitoring of patient health and data quality


• Ensure team compliance with FDA, EMA, ICH, and GCP guidelines


• Conduct literature reviews to identify development opportunities from mechanistic, pharmacological, and clinical perspectives


• Represent clinical science in communications and meetings with regulatory agencies

This role requires:

• M.D. degree (M.D./Ph.D. or prior research experience preferred)


• Board Certification/Eligibility in a relevant therapeutic area (Hepatology, Gastroenterology, Endocrinology, or Nephrology preferred)


• 2-3+ years of clinical practice or industry experience preferred


• Track record of success in clinical or scientific research settings

#MDJOBS, #MDJOBSCD, #GDTherapeuticJobs

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$284,900.00 - $385,700.00