Medical Affairs Manager

MSI Pharma; United States; Hybrid; USD 100,000 - 130,000; Full time

Job summary

A leading biopharmaceutical organization is seeking a Medical Affairs Operations Manager to drive operational excellence in global Medical Affairs activities. This hybrid role involves leadership in planning, budgeting, and execution of Medical Affairs milestones. Candidates should have a Bachelor's degree, over 10 years of experience in related fields, and superb communication skills. This position offers a unique opportunity to impact a global organization immediately.

Qualifications

• 10+ years of experience in Medical Affairs operations, clinical program management, or related roles.
• Ability to lead cross-functional initiatives without direct authority.
• Experience with Gantt planning and executive reporting.

Responsibilities

• Lead and coordinate Medical Affairs Strategy Team forums.
• Establish governance frameworks and escalation pathways.
• Manage Medical Affairs business process calendar.

Skills

Leadership of cross-functional initiatives

Smartsheet

MS Project

Gantt planning

Budget tracking

Excellent written and verbal communication

Education

Bachelor’s degree

Advanced degree or PMP certification

Job description

Medical Affairs Operations Manager (Contract)
Location: King of Prussia, PA
Work Arrangement: Hybrid (3 days onsite per week, flexible onsite days)

We are partnering with a leading biopharmaceutical organization seeking an experienced Medical Affairs Operations Manager to support global Medical Affairs activities within a complex, matrixed environment. This role plays a critical part in driving operational excellence across annual planning, launch readiness, budgeting, and delivery of key Medical Affairs milestones. This is a highly visible role, partnering closely with Disease Area and Regional Medical teams to ensure governance, planning, and execution are delivered on time, in scope, and to a high quality standard.

Key Responsibilities

• Lead and coordinate Medical Affairs Strategy Team (MAST) forums for assigned disease areas, including governance, membership, cadence, and documented outcomes
• Establish clear governance frameworks, RACIs, and escalation pathways across Medical, Clinical, Publications, HEOR, Commercial, and Regional teams
• Own and manage the Medical Affairs business process calendar to ensure timely delivery of insights, evidence generation plans, publication plans, and medical strategy documents
• Implement and maintain standardized global templates for annual planning, launch readiness, and budgeting with strong version control
• Partner with Finance and Disease Area leads to plan, track, reconcile, and report on Medical Affairs budgets
• Develop and manage milestone plans and Gantt schedules, monitoring risks and critical paths
• Support Grants and Investigator Initiated Studies operations, including intake coordination, governance cadence, and milestone tracking
• Ensure compliance with internal SOPs and external standards, maintaining audit ready documentation
• Build dashboards and executive updates to support senior Medical leadership decision making

Required Qualifications

• Bachelor’s degree required; advanced degree or PMP certification preferred
• 10 or more years of experience in Medical Affairs operations, clinical program management, or related pharma or biotech roles
• Proven ability to lead cross functional initiatives without direct authority
• Strong experience with Smartsheet, MS Project, Gantt planning, budget tracking, and executive reporting
• Excellent written and verbal communication skills, with senior leadership exposure

This opportunity is ideal for a seasoned Medical Affairs operations professional looking to make immediate impact within a global organization.