Manufacturing Associate II - 1744 - 175159

Piper Companies; Gaithersburg (MD); On-site; USD 52,000 - 80,000; Full time

Benefits offered by this job

Medical, Dental, Vision through Cigna

401k

Sick leave as required by law

PTO

Holidays

Job summary

Piper Health and Sciences in Gaithersburg, MD is seeking a skilled Manufacturing Associate II to join its biopharmaceutical manufacturing team. You will operate downstream processing equipment, perform chromatography and filtration steps, and maintain cleanroom standards to support production activities.

The role requires GMP experience, 3+ years in biotech/pharma, and a BS in a science discipline. You will document activities, troubleshoot equipment, and ensure product purity through aseptic

Qualifications

• Bachelor's degree in science or related field.
• 3+ years of GMP experience in biotech/pharma with 1+ year in downstream manufacturing.
• Experience with chromatography, filtration, aseptic processing and TFF.

Responsibilities

• Execute manufacturing of drug product following GMP guidelines.
• Prepare buffers and media for downstream processing.
• Operate and maintain chromatography systems for protein purification.
• Perform tangential flow filtration (TFF) and viral filtration.
• Conduct aseptic processing in a clean room with strict contamination control.
• Maintain documentation of manufacturing activities in GMP-compliant records.
• Troubleshoot and resolve downstream processing equipment issues.

Skills

GMP experience

Downstream manufacturing

Chromatography

Filtration

Aseptic processing

TFF

BSC operation

Documentation

cGMP knowledge

Education

Bachelor's degree in science

Tools

Chromatography systems

Filtration equipment

Clean room practice

Job description

Piper Health and Sciences is seeking a skilled and motivated Manufacturing Associate II to join a biopharmaceutical company in the Gaithersburg, MD area. The Manufacturing Associate II is a crucial role in supporting the downstream manufacturing team. This position involves operating and maintaining downstream processing equipment, performing filtration and chromatography techniques and supporting production activities in a cleanroom environment.

Responsibilities of the Manufacturing Associate II:

• Execute manufacturing of drug product following GMP guidelines
• Perform buffer and media preparation for downstream processing.
• Operate and maintain chromatography systems for protein purification.
• Conduct tangential flow filtration (TFF) and viral filtration to ensure product purity.
• Perform aseptic processing in a clean room environment, adhering to strict contamination control measures.
• Maintain accurate documentation of manufacturing activities in compliance with GMP regulations.
• Troubleshoot and resolve issues related to downstream processing equipment.

Qualifications of the Manufacturing Associate II:

• 3+ years of professional experience working in a GMP environment (Biotechnology or Pharmaceutical organization) with 1+ years of experience working in downstream manufacturing
• Experience performing chromatography, filtration techniques, aseptic processing, TFF (tangential flow filtration)
• Experience demonstrating aseptic technique and ability to work in a BSC (biological safety cabinet)
• Understanding of cGMP (current Good Manufacturing Practices)
• Bachelor's degree in science related field

Compensation for the Manufacturing Associate II:

• Salary: $52,000 - $80,000 annually, commensurate with experience
• Comprehensive Benefits: Medical, Dental, Vision (through Cigna), 401k, Sick leave required as by law, PTO, Holidays

This job opens for applications on 9/14/2026. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords:

Manufacturing, manufacturing associate, GMP, good manufacturing practice, cGMP, current good manufacturing practice, TFF, filtration, downstream manufacturing, upstream manufacturing, central service, chromatography skids, process development, facilities, biological safety cabinet, BSC, FDA, biotech, biotechnology, pharmaceutical, pharma, biopharmaceutical, QC, quality control, batch record, SOP, standard operating procedure, log book, equipment calibration, equipment maintenance, autoclave, solution prep, buffer, reagent, sanitize, filter, cell culture, fill finish, column packing, skids, manufacturing, MFG, manufacturing specialist, biopharmaceutical associate, bioprocess associate, manufacturing technical associate, cell therapy, downstream, upstream, Allstream, support service, central service, all stream, cleanroom

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