Manager, Total Rewards & HR Operations

Opus Regulatory, Inc.; Philadelphia (Philadelphia County); Remote; USD 120,000 - 180,000; Full time

Job summary

Opus Regulatory, Inc. is seeking a hands-on Manager, Total Rewards and HR Operations to own and evolve the programs that support employees throughout the employment lifecycle.

Reporting to the Director of Human Resources, this role will have primary responsibility for benefits, payroll, leave administration and related HR operations, while shaping a broader Total Rewards strategy. The ideal candidate will serve as SME for health and welfare programs, multi-state payroll, and compliance, and will

Qualifications

• Experience in total rewards and HR operations.
• Knowledge of ERISA, ACA, COBRA, HIPAA compliance.
• Experience with multi-state payroll.

Responsibilities

• Develop and evolve a cohesive Total Rewards strategy including benefits, compensation, recognition, and well-being.
• Own end-to-end payroll processing for multi-state populations and manage ADP Workforce Now configuration.
• Lead annual benefits open enrollment and renewal planning with HR leadership and Finance.
• Ensure compliance with applicable regulations and provide data-driven insights to HR and leadership.

Job description

Founded in 1994, Opus Regulatory (Opus) is a consultancy providing experts in Regulatory Strategy, CMC, Labeling, and Advertising & Promotion. Our clients range from development-stage biotech companies to mid-size and large pharmaceutical organizations. Backed by Audax Private Equity, Opus has grown to roughly 120 consulting professionals across the US and UK. Our team is made up of biopharmaceutical leaders and innovators, and our mission is to provide the highest level of Regulatory Affairs consultancy in the industry—continually exceeding client expectations through excellence, partnership, and integrity.

Position Overview

Opus Regulatory is seeking a hands-on Manager, Total Rewards and HR Operations to own and evolve the programs and processes that support our employees throughout the employment lifecycle. Reporting to the Director of Human Resources, this role will have primary responsibility for benefits, payroll, leave administration and related HR operations, while partnering with HR leadership to develop a broader Total Rewards strategy.

The role will serve as the subject matter expert and operational owner for Opus's health and welfare programs, including our self-insured/group captive medical plan, as well as multi-state payroll and related compliance. The role will also lead employee communications, wellness and engagement initiatives and provide data and insights to HR and business leadership.

As Opus continues to scale, this position will expand its ownership of compensation, job architecture, pay equity and performance management, creating an opportunity to build a cohesive, competitive and equitable Total Rewards framework in partnership with the Director of HR.

This is an ideal role for an experienced HR professional who enjoys both strategy and execution and is comfortable operating with significant autonomy in a lean, growing organization.

Key Responsibilities

• Partner with the Director of HR to develop and evolve a cohesive Total Rewards strategy—spanning benefits, compensation, recognition, and well-being that aligns with Opus’s business goals, talent needs, and growth plans
• Serve as the subject matter expert on total rewards for HR and business leadership, providing market insights, program recommendations, and cost and competitiveness analysis
• Develop a phased Total Rewards roadmap, prioritizing initiatives as compensation, job architecture, and performance management responsibilities transition to this role
• Support annual benefits and total rewards budgeting and renewal planning with HR leadership and Finance, using claims, utilization, and market data
• Build and maintain total rewards metrics and reporting (e.g., plan costs, utilization, pay and turnover trends), delivering data and insights to HR leadership, Finance, and the board as needed
• Own the day-to-day administration of the company’s health & welfare benefits programs, including medical, dental, vision, life, disability, and ancillary offerings
• Serve as the operational owner of the self-insured/group captive medical plan, directly managing relationships with the benefits broker, captive program manager, third-party administrator (TPA), stop-loss carrier, and network partners
• Monitor plan performance, claims trends, and funding levels in partnership with HR leadership and Finance; support renewal strategy, marketing, and cost analysis
• Lead annual open enrollment, including system configuration, testing, vendor coordination, and post-enrollment audits
• Serve as the primary point of escalation for employee benefits questions and claims issues
• Support administration of the company’s 401(k) plan in coordination with the recordkeeper, advisors, and Finance
• Ensure compliance with ERISA, ACA, COBRA, HIPAA, and other applicable regulations, partnering with Legal and outside advisors as needed
• Design and deliver wellness and well-being initiatives that reflect the needs of a remote, geographically dispersed workforce

Payroll & HR Ops

• Own end-to-end payroll processing for a multi-state (and potentially multi-country) employee and consultant population, ensuring accuracy, timeliness, and compliance with federal, state, and local wage and hour laws
• Serve as primary administrator for the ADP Workforce Now payroll platform, including system configuration, troubleshooting, and ongoing maintenance

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