Manager, Statistics

USA - 3316 Takeda Development Center Americas, Inc.; Cambridge (MA); Hybrid; USD 116,000 - 182,000; Full time

Benefits offered by this job

Medical, dental, & vision insurance

401(k)

Paid time off

Incentive compensation programs

Remote work up to 75%

Job summary

Takeda is seeking a Manager of Statistics in Cambridge, MA to lead the data science function on global project teams supporting pre-clinical and clinical studies. You will influence study design, analysis plans, and reporting while advancing data handling and reproducible research practices.

You will collaborate with scientists across therapeutic areas and with statisticians to address statistical issues, ensuring high-quality, timely deliverables in a hybrid work setting.

Qualifications

• Ph.D. in Statistics or related field.
• Experience with Bayesian hierarchical models, simulations, and predictive inference.
• Ability to design and conduct statistical research projects and communicate results clearly.
• Proficiency in programming with R, Python, SAS and UNIX environments, including HPC.
• Experience applying advanced statistical methods to biomedical data.

Responsibilities

• Independently represent the data science function on global project teams for pre-clinical and clinical studies.
• Lead development and review of study synopsis, protocol, SAP, and clinical study reports.
• Perform end-to-end data analyses from hypotheses through reporting.
• Develop data handling and provenance practices with reproducible research approaches.
• Collaborate across therapeutic areas to define data science goals and endpoints.
• Work with Takeda statisticians to address statistical issues and ensure quality deliverables.

Skills

Bayesian models

Survival analysis

Longitudinal analysis

Deep learning

Reproducible workflows

HPC

Education

Ph.D. in Statistics or related field

Tools

R

Python

SAS

UNIX

High-Performance Computing

Job description

Manager, Statistics

Job Location: Cambridge, MA

Position Description

• independently represent data science function on global project teams in support of pre-clinical and clinical studies and compound level programs;
• play a leadership role in the development and review of the study synopsis, protocol, statistical analysis plan, clinical study report, ensuring accurate and statistically valid deliverables;
• perform end-to-end data analyses, from hypotheses formulation, experimental design, writing analysis plans, data cleaning, executing analysis, and preparing reports and documentation;
• develop and support best data handling and data provenance practices utilizing reproducible, interpretable research approaches;
• strengthen Takeda’s advanced analytics toolkit by identifying and applying emerging techniques, as well as by advancing the state of the art and developing novel analysis tools as needed;
• collaborate effectively within a matrix environment, with scientists in various therapeutic areas to understand disease biology and to identify or develop appropriate goals for data science work (for example identifying sensitive and specific endpoints for segmenting patient population, tracking disease progression, quantifying quality of life, etc.) as well as with colleagues from pharmacology, chemistry, imaging, translational sciences, computational biology, experimental medicine;
• work closely with Takeda statisticians to ensure statistical issues in data analysis are addressed as needed;
• anticipate and communicate internal and external resource and quality issues that may impact deliverables or timelines of the program; propose and implement solutions; escalale issues to management as appropriate in a timely manner;
• increase the internal impact of Takeda’s data science work by identifying opportunities across therapeutic areas; increase the external recognition of Takeda’s data science work by participating in conferences, publishing work and developing external collaborations.

Up to 75% remote work allowed; 5 days onsite work required per month.

Estimated salary range reflects expected pay for this role. Actual base salary depends on the applicant’s qualifications, experience, skills, education, certifications, & work location, & will comply with all applicable minimum‑wage laws.

$116,000 to $182,270 per year.

U.S. employees may be eligible for medical, dental, & vision insurance, 401(k), paid time off, sick leave, company holidays, incentive compensation programs, & other benefits offered under company policies.

Full time.

Worker Type Employee Worker Sub-Type Regular Time Type Full time

Locations Boston, MA; Cambridge, MA

Requirements

• Ph.D. in Statistics or related field.
• Prior experience must include: develop Bayesian hierarchical models incorporating stick-breaking processes and weights for prediction and inference; design and conduct simulations studies to evaluate statistical methods, including defining assumptions, generating data, and summarizing results; conduct independent statistical research projects, including literature review, mathematical derivations of statistical methodology, real-world data application, and preparing written reports or publications; implement reproducible statistical workflows for high dimensional data analysis and methodological evaluation using programming tools (R, Python, SAS) and UNIX operating systems (High-Performance Computing); apply statistical methods and deep learning approaches, including survival analysis, longitudinal data analysis, and deep neural network models, to evaluate hypotheses and interpret results in biomedical and clinical data to cross-functional research teams.

About Takeda

Takeda is an industry-leading, global pharmaceutical company with an unwavering dedication to putting patients at the center of everything we do. We live our values of Takeda-ism – Integrity, Fairness, Honesty, and Perseverance – and are united by our mission to strive towards Better Health and a Brighter Future for people worldwide through leading innovation in medicine. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people’s lives – including your own.

Equal Opportunity

Takeda is an equal opportunity employer.

EOE