Manager/Sr. Manager, Human Resources

Oruka Therapeutics; Menlo Park (CA); Hybrid; USD 146,000 - 187,000; Full time

Benefits offered by this job

Competitive salary

Benefits package

Growth opportunities

Inclusive team

Job summary

Oruka Therapeutics is hiring a Manager/Sr. Manager, Human Resources in a hybrid role based in Menlo Park, CA, with three days onsite per week.

You will support recruiting, onboarding, HR operations, benefits, leave management, compliance, performance management, and employee engagement. The role partners with the Senior Director to deliver operational excellence across the employee lifecycle and continuously improve HR processes and programs.

Qualifications

• 5+ years of progressive Human Resources experience in a biotech/life sciences or fast-paced environment.
• Experience supporting a high-growth startup or publicly traded company is preferred.
• Working knowledge of federal and state employment laws (FLSA, FMLA, ADA).
• Experience supporting benefits administration, leave management, HRIS administration, onboarding, and employee lifecycle processes.

Responsibilities

• Partner with Talent Acquisition and hiring managers to coordinate recruiting, interview scheduling, offer prep, and related activities.
• Coordinate new hire onboarding and orientation for a seamless experience.
• Serve as a point of contact for new hires during onboarding.
• Maintain job descriptions and applicant tracking system information with Talent Acquisition.
• Prepare recruiting reports and hiring metrics as needed.

Skills

HR generalist experience

Employee lifecycle management

Interpersonal communication

Confidentiality

Tools

HRIS

Applicant Tracking System

Microsoft Office

PEO collaboration

Job description

Manager/Sr. Manager, Human Resources

Location: Hybrid - Menlo Park, CA (3 days onsite/week)

Reporting to the Senior Director, Human Resources, the Manager/Sr. Manager, Human Resources will serve as a trusted HR generalist who supports the day‑to‑day execution of key HR programs and operations. This hands‑on role partners closely with the Senior Director to deliver operational excellence across the employee lifecycle, including recruiting support, onboarding, HR operations, benefits administration, leave management, compliance, performance management administration, and employee engagement.

The ideal candidate is an organized, collaborative HR professional who enjoys working in a growing organization, exercises sound judgment, and is committed to providing outstanding service to employees and managers while continuously improving HR processes and programs.

Key Responsibilities

• Partner with the Talent Acquisition team and hiring managers to coordinate recruiting activities, interview scheduling, offer preparation, and other aspects of the hiring process.
• Coordinate new hire onboarding and orientation to ensure a seamless and engaging employee experience.
• Serve as a primary point of contact for new hires during the onboarding process.
• Maintain job descriptions and applicant tracking system information in partnership with Talent Acquisition.
• Prepare recruiting reports and hiring metrics as needed.

HR Operations

• Serve as a resource for employees by responding to routine HR‑related questions and directing more complex matters to the Senior Director, Human Resources as appropriate.
• Support the Senior Director and managers in the consistent administration and communication of HR policies, programs, and processes.
• Coordinate performance management activities, including review cycles, goal‑setting processes, communications, and documentation.
• Maintain HRIS data integrity and prepare reports, metrics, and analytics as needed.
• Administer employee lifecycle transactions, including hires, promotions, transfers, status changes, and separations.
• Maintain personnel files and HR documentation in compliance with company policies and applicable regulations.
• Coordinate HR compliance activities, including I‑9 administration, personnel record audits, required postings, recordkeeping, and support for policy updates.
• Assist with planning and executing employee engagement initiatives, recognition programs, learning opportunities, and company events.
• Identify opportunities to improve HR processes, workflows, and employee experience through continuous process improvement.

Benefits & Leave Administration

• Coordinate benefits administration in partnership with the company’s PEO and benefit providers.
• Serve as the primary internal contact for employee benefits questions and support annual open enrollment activities.
• Coordinate leave of absence administration, including FMLA, ADA, parental leave, disability, and applicable state and local leave programs.
• Track leave requests, documentation, eligibility, and return‑to‑work activities while partnering with the PEO, payroll, employees, and managers to ensure accurate administration.
• Support compliance with applicable federal, state, and local employment laws related to benefits and leave administration.

Qualifications

• 5+ years of progressive Human Resources experience, preferably as an HR Generalist or HR Operations professional in a biotech, life sciences, or other fast‑paced environment.
• Experience supporting a high‑growth startup or publicly traded company is preferred.
• Working knowledge of federal and state employment laws, including FLSA, FMLA, ADA, and related regulations.
• Experience supporting benefits administration, leave management, HRIS administration, onboarding, and employee lifecycle processes.
• Strong organizational and project management skills with the ability to manage multiple priorities and deadlines.
• Excellent interpersonal, written, and verbal communication skills and the ability to handle confidential information with discretion.
• Strong customer service orientation with the ability to build effective working relationships across all levels of the organization.
• Proficiency with Microsoft Office and HRIS platforms; experience working with a PEO and applicant tracking systems is preferred.
• Comfortable working in a dynamic, high‑growth environment where priorities evolve quickly.

Compensation

An appropriate compensation package will include a competitive base salary, equity, and performance‑based bonus opportunity.

The anticipated salary range for Manager level is $146,000–$161,000 and Sr. Manager level is $161,000–$187,000, with final compensation determined based on experience, qualifications, and other job‑related factors.

Salary Range For the Role

$146,000 – $187,000 USD

What We Offer

• A chance to be part of a vibrant startup culture where your work can directly impact bringing new medicines to patients.
• Competitive salary and benefits package.
• A supportive and inclusive team environment where everyone is encouraged to bring their authentic selves to work.
• Opportunities for professional growth and development.

As set forth in Oruka Therapeutics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.