Manager of Bioinformatics (Oncology Product Development)

Natera; San Carlos (CA); On-site; USD 154,000 - 193,000; Full time

Benefits offered by this job

Annual bonus

Long-term equity awards

401(k) with company match

Generous paid time off

Wellness and work-life benefits

Job summary

Natera in California is seeking a Manager of Bioinformatics to lead the Bioinformatics team focused on Oncology Product Development. You will guide the design, development and validation of ctDNA-based diagnostic tests and collaborate across biostatistics, molecular biology, software engineering and commercial groups.

The ideal candidate will have a strong bioinformatics and data science background with leadership experience, and a track record in LDT assay development or related areas.

Qualifications

• Minimum 4-8 years of post-graduate experience in data science or bioinformatics.
• 1-3 years of experience as technical lead in diagnostics or related field.
• Experience moving algorithm-based products through commercialization and launch.

Responsibilities

• Provide technical leadership for product development projects across cross-functional teams.
• Lead optimization of workflows and analysis pipelines for diagnostic tests.
• Supervise bioinformatics and data science staff and develop their skills.
• Provide input on experimental design, analysis and interpretation.
• Set standards for rigorous data analysis and documentation.
• Contribute to intellectual property and strategic project milestones.

Skills

Python/R

Statistics & ML

NGS analysis

Team leadership

Job description

Manager of Bioinformatics (Oncology Product Development)

Natera is currently seeking a Bioinformatics Manager to join the Bioinformatics team focused on Oncology Product Development. In this role, the individual will manage a team of Bioinformaticians and Data Scientists and provide technical leadership in the design, development and validation of ctDNA-based diagnostic tests. This position requires extensive cross-functional collaboration with biostatistics, molecular biology, software engineering and commercial departments. The ideal candidate will have a strong background in bioinformatics and data science, optimally with experience in the LDT assay development space, and an established record of project and technical leadership.

PRIMARY RESPONSIBILITIES:

• Provide technical leadership for product development projects by representing the bioinformatics team in cross-functional interactions and moving products through the full development process through validation and commercial launch.


• Lead the effort to optimize workflows, improve tools and pressure test analysis pipelines for diagnostic tests, including the detection of cancer-associated variants and the implementation of evidence-based quality control thresholds.


• Supervise bioinformatics scientists and data scientists, managing their technical contributions, prioritizing resources, and taking responsibility for their technical and professional development.


• Provide input on experiment design, analysis and interpretation based on expert understanding of Natera’s technology and relevant mathematical principles.


• Work at a high level of independence and responsibilities in carrying out assignments.


• Contribute to our intellectual property portfolio.


• Set standards for rigorous data analysis and lead the production of high-quality documentation.

QUALIFICATIONS:

Requirements:

• Minimum of 4-8 years of post-graduate experience in a data science and/or bioinformatics role and 1-3 years of experience as technical lead in diagnostics or a related field


• Experience moving algorithm-based products through commercialization and launch in a medical or biological application such as diagnostic testing, medical imaging, or biotechnology


• 1-2 years of management experience leading a technical team with demonstrable evidence of leadership and team management skills.

Desirable, but not required:

KNOWLEDGE, SKILLS, AND ABILITIES:

• Experience using Python or R for scientific data analysis and visualization.


• Strong foundation in statistical modeling/machine learning, including probability theory and estimation/classification methods.


• Experience with analysis of next-generation sequencing data, preferably including algorithm development or optimization.


• Proven ability to apply mathematical principles to solve real estimation problems and implement practical solutions.


• Excellent analytical, problem-solving and decision-making skills to independently make sound judgments and find creative solutions to moderately complex problems.


• Experience leading technical projects, including defining and meeting project milestones, delegating tasks to more junior team members, and ensuring the quality of technical deliverables.


• Excellent communication skills and the desire to work in a dynamic and collaborative environment.

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

Annual performance incentive bonus

Long-term equity awards

401(k) with company match

Generous paid time off and company holidays

Additional wellness and work-life benefits

Compensation Range

$154,000 - $192,500 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Natera’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A \"disabled veteran\" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

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An \"Armed forces service medal veteran\" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.