Manager of Statistical Programming

Natera; San Carlos (CA); On-site; USD 145,000 - 182,000; Full time

Benefits offered by this job

Annual incentive bonus

Long-term equity awards

401(k) with company match

Generous paid time off

Wellness benefits

Job summary

Natera is seeking a Manager of Statistical Programming to lead ADS and TLF, oversee regulatory submissions, and build R packages and Shiny dashboards in support of oncology diagnostics.

The role combines strategic leadership with hands-on programming in a fast-paced, cross-functional environment, offering growth opportunities, competitive benefits, and the chance to influence data-driven decisions across multiple trials.

Qualifications

• Bachelor’s degree in statistics, mathematics, computer science, or related field.
• 5+ years of related experience, with at least 3 years in clinical trial analysis.
• At least 3 years of R programming experience, including package development.

Responsibilities

• Lead and oversee statistical programming deliverables, including ADS and TLF, ensuring data integrity and regulatory compliance.
• May manage a team of statistical programmers and contribute hands-on to programming work.
• Lead regulatory submissions (e.g., 510(k), CTA/CDx, PMA) and maintain rigorous global standards.
• Develop R packages and Shiny dashboards to support data review and study monitoring.
• Promote best practices in statistical programming development and validation.
• Collaborate cross-functionally with Biostats, Data Management, and Clinical Science.

Skills

R programming

Clinical trial analysis

Team leadership

Education

Bachelor’s in Statistics, Mathematics, Computer Science, or related field

Job description

This is an exciting opportunity to participate in advancing Natera’s oncology product portfolio of cutting‑edge diagnostic tests. As Manager of Statistical Programming, you will leverage your strong R programming skills and clinical trials background to contribute to the analysis and reporting of clinical trials supporting multiple regulatory submissions.

Primary Responsibilities:

• Lead and oversee statistical programming deliverables, including ADS (Analysis Datasets) and TLF (Table, Listings and Figures), ensuring data integrity and regulatory compliance with ICH, GCP, and FDA 21 CFR Part 11.
• May manage a team of statistical programmers, taking responsibility for their technical and professional development, while contributing hands‑on to programming work.
• Act as primary programming lead for regulatory submissions (e.g., 510(k), CTA/CDx, and PMA), ensuring all deliverables meet rigorous global standards.
• Maintain programming infrastructure, including R package development, validation, and maintenance in a controlled environment.
• Develop R Shiny dashboards that support data review, study monitoring, and exploration of analysis results.
• Promote statistical programming development and validation best practices.
• Work cross‑functionally with Biostats, Data Management, Clinical Science, and other functions as necessary.

Qualifications:

• Bachelor’s in Statistics, Mathematics, Computer Science, or a related field.
• 5+ years of related experience, with at least 3 years of experience in Clinical Trial analysis.
• At least 3 years of R programming experience, including package development.

Knowledge, Skills, and Abilities:

• Proficient in R programming, including building and maintaining packages.
• Experience in analysis dataset and TLF generation.
• Prior experience in NGS, genetics, and/or oncology diagnostics preferred.
• Experience maintaining statistical computing environments a plus.

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonablyexpect to offer at the time of hire.Final compensation will vary based on experience, qualifications, and internal equity considerations.

This positionis also eligible for additional compensation and benefits throughNatera’s robust Total Rewards program, including:

Annual performance incentive bonus

Long‑term equity awards

401(k) with company match

Generous paid time off and company holidays

Additional wellness and work‑life benefits

Compensation Range

$145,200 - $181,500 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell‑free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world‑class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Natera’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service‑connected disability.

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An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.