Manager, Global Order-to-Cash (O2C)

Arrowhead Pharmaceuticals; Madison (WI); On-site; USD 120,000 - 150,000; Full time

Job summary

Arrowhead Pharmaceuticals, Inc. is seeking a strategic Manager, Order-to-Cash to lead the global O2C function from Verona, WI. This full-time onsite role partners with Commercial, Market Access and Finance to ensure compliant revenue operations during a scale-up of the company’s first commercial launch.

The candidate will optimize O2C processes, implement Dynamics 365, and drive automation and controls across the revenue cycle in a highly regulated biopharma environment.

Qualifications

• Bachelor's degree in Finance, Accounting, Business Administration, Life Sciences, or related field.
• Five years of progressive experience in O2C, Revenue Operations, Finance Operations, or Shared Services.
• Experience building, optimizing, and scaling O2C functions within biotechnology, pharmaceutical, medical device, or other highly regulated industries.
• Significant ERP implementation, optimization, or transformation experience, preferably with Microsoft Dynamics 365.
• Strong understanding of revenue cycle processes and SOX compliance requirements.
• Proven ability to work independently, prioritize competing priorities, and manage multiple projects and timelines.
• Excellent communication and interpersonal skills with the ability to influence across multiple levels of the organization.
• Intermediate to advanced proficiency in Microsoft Office applications, including Excel, Word, Outlook, and PowerPoint.
• Experience with chargebacks, rebates, distributor fee-for-service arrangements, and market access programs (preferred).

Responsibilities

• Develop the global O2C strategy, operating model, and roadmap to support product distribution and growth.
• Build scalable processes and controls for expansion and new product launches.
• Own O2C policies, performance metrics, and continuous improvement initiatives.
• Partner with Commercial, Market Access, and Finance to onboard customers, contract, price, and service processes.
• Lead the implementation, optimization, and governance of O2C in Dynamics 365 and related systems.
• Define and execute automation initiatives via EDI, workflow automation, and system integrations.
• Maintain SOX-compliant controls across all O2C activities.

Skills

O2C

SOX

ERP systems

Dynamics 365

Process improvement

Education

Bachelor's degree in Finance/Accounting/Business Administration/Life Sciences

MBA or professional certification (preferred)

Tools

Dynamics 365

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

Arrowhead Pharmaceuticals is seeking a strategic and experienced Manager, Order-to-Cash (O2C) to help establish, lead, and scale the global O2C function in support of the company's first commercial product launch and future growth initiatives. This role is responsible for supporting the vision, strategy, governance, and execution of end-to-end commercial revenue cycle processes while ensuring operational excellence, scalable infrastructure, strong internal controls, and exceptional customer service.

As a key member of the Finance organization, the Manager will optimize O2C operations, develop cross-functional operating models, and serve as a trusted business partner to Commercial, Supply Chain, Market Access, Legal, Accounting, and external trading partners. The ideal candidate brings expertise in life sciences commercialization, commercial product launches, and finance transformation, with experience implementing processes, systems, and controls that support business growth and compliance.

This role is full-time onsite, 5 days a week in Verona, WI.

Responsibilities

Strategy, Leadership & Business Partnership

• Support the development and execution of the global O2C strategy, operating model, and roadmap to support commercial product distribution and business growth.
• Build and enhance scalable processes and controls that support global expansion, new product launches, and increasing transaction complexity.
• Own O2C policies, performance metrics, and continuous improvement initiatives.

Commercial Launch & Operations

• Partner with Commercial, Market Access, and Finance leadership to develop customer onboarding, contracting, pricing administration, and customer service processes.
• Ensure commercial agreements, customer terms, rebate programs, and related activities are effectively operationalized and executed in compliance with company policies.

Systems, Transformation & Process Excellence

• Lead the implementation, optimization, and governance of O2C capabilities within Microsoft Dynamics 365 and related commercial systems.
• Define and execute automation initiatives utilizing EDI, workflow automation, system integrations, analytics, and emerging technologies.

Controls and Compliance

• Partner with Internal Audit and External Audit teams to maintain effective controls and ensure SOX compliance across all O2C activities.

Requirements

• Bachelor's degree in Finance, Accounting, Business Administration, Life Sciences, or a related field.
• Five years of progressive experience in O2C, Revenue Operations, Finance Operations, or Shared Services.
• Experience building, optimizing, and scaling O2C functions within biotechnology, pharmaceutical, medical device, or other highly regulated industries.
• Significant ERP implementation, optimization, or transformation experience, preferably with Microsoft Dynamics 365.
• Strong understanding of revenue cycle processes and SOX compliance requirements.
• Proven ability to work independently, prioritize competing priorities, and manage multiple projects and timelines.
• Excellent communication and interpersonal skills with the ability to influence across multiple levels of the organization.
• Intermediate to advanced proficiency in Microsoft Office applications, including Excel, Word, Outlook, and PowerPoint.

Preferred

• MBA or other relevant professional certification.
• Experience with chargebacks, rebates, distributor fee-for-service arrangements, and market access programs.

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.