Long-Read Sequencing Co-op: Bioinformatics & Stem Cells

Vertex Pharmaceuticals

Boston (MA)

On-site

USD 48,000 - 69,000

Full time

5 days ago
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Benefits offered by this job

Free gym access
Free meals
Commuter benefits
Career development opportunities
Intern-only events

Job summary

Vertex Long Read Sequencing Co-Op is a 6-month experiential training program for students pursuing an advanced degree in Biological Sciences or related fields. You will work on RNA sequencing applications, plasmid integration analyses, and direct RNA sequencing to support monoclonal antibody projects.

The program emphasizes mentorship, flexible options, and exposure to CGT AD workflows in a collaborative Boston environment.

Qualifications

  • Master's or PhD in Systems Biology, Computational Biology, Developmental Biology, or related field.
  • Experience with long-read sequencing workflows and data analysis.
  • Proficiency in Python or R, and Linux environments.
  • Familiarity with bioinformatics tools such as minimap2 and samtools.

Responsibilities

  • Perform RNA sequencing and plasmid integration analyses to support monoclonal antibody projects.
  • Prepare sequencing libraries and evaluate dataset quality and integrity.
  • Analyze data with DESeq2 and GSEA to derive biological insights.
  • Present results and contribute to method development and optimization.

Skills

Nucleic acid extraction
cDNA preparation
Sequencing library prep
Experiment design
Oxford Nanopore
Python
R
Linux
Minimap2
Samtools
DESeq2
GSEA

Education

Master's / PhD in Systems Biology or related

Tools

Minimap2
Samtools
DESeq2

Job description

Vertex Long Read Sequencing Co-Op is a 6-month experiential training program for students pursuing an advanced degree in Biological Sciences or related fields. You will work on RNA sequencing applications, plasmid integration analyses, and direct RNA sequencing to support monoclonal antibody projects.

The program emphasizes mentorship, flexible options, and exposure to CGT AD workflows in a collaborative Boston environment.

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