LNP Lab Technician

GenScript/ProBio; Redmond (WA); On-site; USD 55,000 - 65,000; Full time

Benefits offered by this job

Medical, dental, and vision insurance

401(k) retirement plan with company match

Paid parental leave

Flexible spending and health savings accounts

On-site gyms

Paid time off policy including vacation and personal days

Job summary

GenScript/ProBio in Redmond, Washington is seeking a skilled professional for a role focused on the encapsulation and purification of mRNA and genetic payloads. The successful candidate will perform complex processes, adhere to quality standards, and work collaboratively within a dedicated team.

The position offers a salary range of $55,000 – $65,000, along with a comprehensive benefits package including medical, dental, and retirement plans.

Qualifications

• Prior experience working with mRNA or Lipid Nanoparticles is a plus.
• Experience in a fast-paced, high-demand environment.
• Technical proficiency in enzymatic reactions is desired.

Responsibilities

• Expertly encapsulate genetic payloads within various lipids.
• Perform LNP purification and concentration.
• Conduct quality checks on particle size and zeta potential.
• Maintain comprehensive records in compliance with ISO 9001.

Skills

Advanced Payload Encapsulation

Precise Purification and Concentration

Nanoparticle Quality Assurance

Standard Operating Procedures Compliance

Team Collaboration

Effective Communication

Education

Bachelor's degree in Chemical Engineering, Biology, or related field

Tools

PCR

HPLC

Job description

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotechnology and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions.

As a key member of our team, you will have the opportunity to work on exciting projects involving the encapsulation and purification of mRNA and genetic payloads, ensuring the highest quality standards throughout the entire process.

Key Responsibilities

• Advanced Payload Encapsulation: Expertly encapsulate a range of genetic payloads, including mRNA, Circular RNA, and sgRNA, within a diverse array of lipids.
• Precise Purification and Concentration: Follow LNP downstream processing SOP to perform LNP purification and concentrating. Related technical skill include but not limit to ultrafiltration, TFF, sterile filtration, and FPLC methods.
• Performing complicate antibody decorated LNP process and related purification process following SOP guidance
• In process QC for LNP size, zeta, PDI, encapsulation efficiency measure and others, make sure following good documentation rule and take care for details
• Nanoparticle Quality Assurance: Conduct quality checks on particle size and zeta potential to ensure the highest standards of quality and performance.
• Final Product Preparation: Prepare the final product for shipment, including filtering, aliquot filling, and affixing labels to shipping tubes.
• Standard Operating Procedures (S.O.P.) Compliance: Strictly adhere to production S.O.P.s to maintain consistency, quality to validated processes.
• Thorough Documentation: Maintain comprehensive records accordance to ISO 9001 of all processes and materials used in the production.
• Inventory Management: Keep track of inventory using our management system, and proactively order materials as needed for production.
• High Throughput and Accuracy: Quickly and accurately perform tasks in high repetition.

Qualifications

• Educational Background: Possess a Bachelor's degree in Chemical Engineering, Biology, or a related field in Chemistry.
• Relevant Experience: Prior experience working with mRNA or Lipid Nanoparticles (LNP) is a definite plus.
• Technical Proficiency: Experience with techniques such as PCR, HPLC, or enzymatic reactions is highly desired.
• Team Collaboration: The ability to work effectively as part of a small cross-disciplinary team is essential to achieve both short-term and long-term goals.
• Adaptability: Experience in a fast-paced, high-demand environment is highly desirable.
• Effective Communication: The capability to communicate with peers and managers in a polite and concise manner is a valuable asset.

Compensation

Salary range: $55,000 – $65,000 total compensation, including bonus, depending on experience and qualifications.

Benefits

• Medical, dental, and vision insurance.
• 401(k) retirement plan with a company match that vests fully on day one.
• Paid parental leave after just three months of employment.
• Paid time off policy that includes vacation time, personal time, sick time, floating holidays, and company holidays.
• Flexible spending and health savings accounts.
• Life and AD&D insurance.
• Short- and long-term disability coverage.
• Legal assistance.
• Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance.
• Commuter benefits.
• Well-being initiatives.
• Peer-to-peer recognition programs.

Employee Perks

• On-site gyms.
• Jury Duty Leave.
• Compassionate Leave.
• Personal days.
• Paid sick days (earned based on hours worked).
• Paid Company Holidays per year.
• Paid Time Off.
• Short Term Disability Insurance.
• New Child Leave.

Equal Opportunity Employer

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.