LNP Formulation Scientist I

IT Engagements, Inc.; San Diego (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

IT Engagements seeks a motivated Scientist 1 to join the Formulation team. You will formulate and optimize lipid nanoparticles (LNPs) for nucleic acid delivery, working with senior scientists and cross-functional teams to execute DoE-based campaigns and analyze data.

Ideal candidates have 4+ years in biopharma with LNP expertise, strong Excel and data-analysis skills, and a collaborative, detail-oriented mindset in a fast-paced environment. Position based in San Diego, CA; immediate opening.

Qualifications

• Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, or related discipline with 4+ years of biopharma industry experience.
• Master's degree with 1+ years of industry experience.
• 2+ years hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids.
• Proficiency with DLS, Zeta potential, and Ribogreen assays.
• High proficiency in MS Excel; experience with JMP or Prism preferred.
• Attention to detail, reproducible data, strong organizational skills, and teamwork.
• Experience with targeted LNP preparation and immune cell delivery desirable.

Responsibilities

• Execute and optimize the formulation and characterization of lipid nanoparticles (LNPs) or targeted LNPs encapsulating nucleic acids for in vitro and in vivo studies.
• Implement Design of Experiment (DoE) based screening campaigns to optimize LNP compositions and processing parameters.
• Collaborate cross-functionally with internal teams to support and fulfill formulation requests.
• Support early-stage formulation development and downstream processing activities when needed, including cryoprotection, scale-up, and stability studies.
• Maintain detailed records documenting formulation activities and results.
• Analyze, interpret, and present experimental data to the formulation team.
• Contribute to routine lab management activities, including inventory tracking, supply ordering, buffer preparation, and autoclaving.

Skills

LNP formulation

Analytical skills

Excel proficiency

Data analysis software

Education

Bachelor's degree in Chemistry/Biochemistry/Chemical Engineering

Master's degree in relevant field

Tools

DLS

Zeta potential

Ribogreen assays

JMP

GraphPad Prism

Job description

IT Engagements seeks a motivated Scientist 1 to join the Formulation team. You will formulate and optimize lipid nanoparticles (LNPs) for nucleic acid delivery, working with senior scientists and cross-functional teams to execute DoE-based campaigns and analyze data.

Ideal candidates have 4+ years in biopharma with LNP expertise, strong Excel and data-analysis skills, and a collaborative, detail-oriented mindset in a fast-paced environment. Position based in San Diego, CA; immediate opening.