Lead Translational Medicine Scientist – Early Clinical Development

Merck & Co.; South San Francisco (CA); Hybrid; USD 260,000 - 410,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) retirement plan

Paid holidays

Vacation

Job summary

Merck & Co. in South San Francisco, CA seeks a physician-scientist to join as Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development within Infectious Diseases.

Lead early development from preclinical to Phase 2, collaborating with discovery and late-stage teams to drive pharmacology, biomarkers, and cross-functional programs. MD or MD/PhD with translational research experience required.

Qualifications

• MD or MD/PhD with translational/clinical research experience.
• Ability to lead early clinical development strategy from preclinical through Phase 2.
• Experience in infectious diseases translational medicine.
• Strong collaboration with cross-functional teams across discovery, translational, and clinical groups.
• Engagement with external thought leaders and scientific communications.

Responsibilities

• Lead early clinical development strategy from preclinical to Phase 2.
• Collaborate with discovery, pharmacology, toxicology and other teams to advance programs.
• Design and execute early development plans with internal and external staff.
• Lead clinical pharmacology studies across all phases and DDI studies.
• Support regulatory filings with supportive documents and presentations.
• Develop and validate clinical biomarkers and platforms.
• Engage with external partners and present at conferences.
• Work with global teams across sites.

Skills

Clinical Research

Early Clinical Development

Infectious Disease

Translational Medicine

Education

MD or MD/PhD

Job description

Merck & Co. in South San Francisco, CA seeks a physician-scientist to join as Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development within Infectious Diseases.

Lead early development from preclinical to Phase 2, collaborating with discovery and late-stage teams to drive pharmacology, biomarkers, and cross-functional programs. MD or MD/PhD with translational research experience required.