Director, Translational Medicine — Infectious Diseases

Merck & Co.; West Point (PA); Hybrid; USD 260,000 - 410,000; Full time

Benefits offered by this job

Medical benefits

Dental benefits

Vision benefits

401(k)

Job summary

Merck & Co., Inc. invites applications for a Physician-scientist to join Translational Medicine as a Principal Scientist (Clinical Director) in Early Clinical Development for Infectious Diseases.

The role leads strategy from preclinical through Phase 2/POC and collaborates with discovery, pharmacology, toxicology, regulatory affairs, and global trials teams. MD or MD/PhD required with strong translational research background and cross-functional leadership.

Qualifications

• MD or MD/PhD degree required.
• Experience in translational research and early clinical development.
• Ability to lead cross-functional teams.

Responsibilities

• Lead clinical pharmacology studies for programs across all phases (I–IV).
• Design and execute early development strategies with internal and external staff.
• Collaborate with discovery sciences, pharmacology, toxicology, and regulatory affairs to advance therapeutics.
• Develop biomarker strategies to support translational insights and decision-making.
• Engage with external thought leaders and present data at conferences.
• Support regulatory filings with clinical pharmacology data and reports.

Skills

Clinical Research

Early Clinical Development

Infectious Disease

Translational Medicine

Education

MD or MD/PhD

Job description

Merck & Co., Inc. invites applications for a Physician-scientist to join Translational Medicine as a Principal Scientist (Clinical Director) in Early Clinical Development for Infectious Diseases.

The role leads strategy from preclinical through Phase 2/POC and collaborates with discovery, pharmacology, toxicology, regulatory affairs, and global trials teams. MD or MD/PhD required with strong translational research background and cross-functional leadership.