Lead Scientist, Protein Immunotherapy

Scripps Research Translational Institute

San Diego (CA)

Hybrid

USD 120,000 - 150,000

Full time

28 hours ago
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Benefits offered by this job

Retirement plans
Health and Welfare plans
FSAs
Vacation and sick leave
Counseling services
On-site parking

Job summary

Calibr-Skaggs Institute for Innovative Medicines, part of Scripps Research, seeks a Principal Scientist in Protein Immunotherapy to translate protein therapies from ideation to first-in-human trials. You will work on multi-specific antibodies to control immune pathways in cancer and inflammatory diseases, with opportunities to explore broader portfolio ideas.

The role requires leading entry-level researchers, training, and delivering experimental results through collaborative scientific effort

Qualifications

  • PhD strongly preferred with 10+ years of industry experience.
  • Hands-on experience in primary human immune cells and immuno-oncology.
  • Experience with protein engineering and antibody design/characterization.
  • Strong documentation, collaboration, and cross-functional skills.

Responsibilities

  • Design and execute immune profiling projects and assays.
  • Develop antibody-based therapeutics including bispecifics.
  • Lead a team of PhD-level scientists and present findings.
  • Coordinate with cross-functional teams and manage project goals.

Skills

Immunology
Flow cytometry
Cell culture
Antibody design
Genomic data analysis
Gene editing (CRISPR/TALEN)
High-throughput screening
Project leadership
Cross-functional collaboration

Education

PhD in Immunology/Related field
Bachelor’s degree in Biology/Biochemistry or related

Tools

CRISPR
TALEN
Flow cytometer hardware
Automation systems

Job description

Calibr-Skaggs Institute for Innovative Medicines, part of Scripps Research, seeks a Principal Scientist in Protein Immunotherapy to translate protein therapies from ideation to first-in-human trials. You will work on multi-specific antibodies to control immune pathways in cancer and inflammatory diseases, with opportunities to explore broader portfolio ideas.

The role requires leading entry-level researchers, training, and delivering experimental results through collaborative scientific effort

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