Lead Scientist, Protein Formulations & Biopharmaceuticals

Johnson & Johnson Co.; Malvern (Chester County); On-site; USD 120,000 - 170,000; Full time

Job summary

Johnson & Johnson in Malvern, PA seeks a Principal Scientist, Protein Formulations to lead lab-based studies in pre-formulation and formulation of biologics including mAbs. You will design experiments, analyze complex datasets, and communicate results to cross-functional teams while advancing DPD&D efforts.

The candidate will have a PhD (or MS with extended experience) and a track record in protein stability, biophysics, and regulatory readiness, with strong technical writing and collaboration

Qualifications

• PhD in Biomedical Engineering, Chemical Engineering, Pharmaceutical Sciences, Biophysics, or Chemistry with 3+ years of experience, or MS with 6+ years.
• Strong knowledge of protein stability, thermodynamics, and biophysical characterization.
• Experience with protein biophysical characterization and chromatography techniques such as HPLC, fluorescence and UV spectroscopy, light scattering (SLS, DLS).
• Ability to identify protein liabilities and developability assessments for products from pre-clinical to commercial readiness.
• Ability to interpret and analyze data from biophysical and biochemical assays and design appropriate experiments.
• Technical writing skills and experience with regulatory filings preferred.

Responsibilities

• Design, execute, analyze, and document studies to develop formulations for biologic therapeutics.
• Interpret complex datasets and effectively communicate impact to stakeholders.
• Evaluate and develop technologies in emerging drug delivery to enhance the protein portfolio.

Skills

Analytical Reasoning

Biochemistry

Biotechnology

Chemistry

Education

PhD in Biomedical Engineering, Chemical Engineering, Pharmaceutical Sciences, Biophysics, Chemistry

MS with 6+ years of industry experience

Tools

HPLC

Fluorescence

UV Spectroscopy

Light Scattering

Job description

Johnson & Johnson in Malvern, PA seeks a Principal Scientist, Protein Formulations to lead lab-based studies in pre-formulation and formulation of biologics including mAbs. You will design experiments, analyze complex datasets, and communicate results to cross-functional teams while advancing DPD&D efforts.

The candidate will have a PhD (or MS with extended experience) and a track record in protein stability, biophysics, and regulatory readiness, with strong technical writing and collaboration