Lead Scientist, Preventive Cancer Vaccines

BioSpace

Englewood (NJ)

On-site

USD 165,000 - 215,000

Full time

5 days ago

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Job summary

ICR is seeking a Principal Scientist to lead the Cancer Prevention Group, focusing on peptide-based and neoantigen cancer vaccines. The role will oversee preclinical design, execution, and interpretation, guiding translational progress to human studies.

Collaboration with CROs and external KOLs is essential to advance first-in-class preventive vaccine programs. The candidate should hold a PhD or MD with 10+ years in vaccine R&D, with deep expertise in cancer immunology, immuno-oncology, and

Qualifications

PhD or MD with at least 10 years of vaccine development experience, preferably cancer vaccines.
Strong expertise in personalized cancer vaccines and neoantigen-based strategies.
Experience with vaccine epitope identification, selection, adjuvants, and immune monitoring.
Proficiency in TCR repertoire analysis, cytokine release and ELISPOT assays.
Ability to derive antigen-specific T cell clones/lines and work with external partners.

Responsibilities

Lead ICR's Cancer Prevention Group in researching and developing preventive cancer vaccines.
Drive end-to-end design, execution and interpretation of preclinical vaccine studies.
Collaborate with external KOLs and CRO partners to translate findings into programs.