Lead Scientist, Pharmacokinetics & DMPK

MSD; Pennsylvania; Hybride; USD 142 000 - 224 000; Plein temps

Avantages offerts par ce poste

Medical, dental, vision insurance

401(k) retirement plan

Paid holidays

Vacation and sick days

Résumé du poste

MSD West Point seeks an Associate Principal Scientist in Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics. You will drive DMPK-focused discovery and translational modeling for diverse therapeutics, collaborating across disciplines and guiding PK/PD strategy and DDI risk assessment.

The role emphasizes leadership, cross-functional teamwork, and strong communication to support regulatory filings and clinical development decisions in a fast-paced environment.

Qualifications

• B.S. or Master’s with 8+ years relevant experience, or Ph.D. with 5+ years of industry experience in therapeutics discovery and development.
• Experience integrating preclinical DMPK and pharmacology to enable translational modeling and simulation for dose selection, PK/PD, and safety.
• Experience with authoring documents in support of IB, IND, and regulatory inquiries.
• Demonstrated leadership and collaboration across multidisciplinary discovery and development teams.

Responsabilités

• Collaborate in fast-paced, cross-functional teams to advance discovery and clinical development of therapeutics.
• Guide design and interpretation of in silico, in vitro, and in vivo analyses for DMPK profiling.
• Assess DDI risk using static and PBPK models and advise on DDI strategies.
• Author reports and documents to support regulatory filings (IB/IND/WMA).
• Identify program risks and develop mitigation strategies to enable progress.

Connaissances

Bioanalytical Techniques

Cell-Based Assays

Clinical Development

DMPK

Drug Development

Flow Cytometry

Immunoassays

LC-MS

Formation

Pharmaceutical Sciences / Pharmacology / Biomedical Engineering / Biochemistry

Description du poste

MSD West Point seeks an Associate Principal Scientist in Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics. You will drive DMPK-focused discovery and translational modeling for diverse therapeutics, collaborating across disciplines and guiding PK/PD strategy and DDI risk assessment.

The role emphasizes leadership, cross-functional teamwork, and strong communication to support regulatory filings and clinical development decisions in a fast-paced environment.