Lead QC Analytical Scientist: Method Validation & Mentoring

Promega; Madison (WI); On-site; USD 90,000 - 120,000; Full time

Job summary

Promega in Madison, WI seeks a QC Analytical Scientist 3 to perform complex analytical testing for API release and stability; participate in method development, validation, and training. You will be a key team member applying chemistry knowledge to support QC and manufacturing.

You will validate methods, lead OOS investigations, draft QC procedures, mentor junior staff, maintain instrumentation, and leverage digital tools including AI to improve efficiency and compliance.

Qualifications

• BS in Chemistry or related field with 3+ years QC experience, or MS with 2+ years QC experience.
• Independent method validation and characterization.
• Strong knowledge of analytical instrumentation (HPLC, LC-MS, GC, NMR, ICP-MS, Karl Fischer, XR-PD, FTIR, spectrophotometers).
• Proficiency with statistical analysis tools (mean, SD, regression, confidence intervals).
• Experience mentoring or training staff.
• Proficiency with digital tools and technology, including Microsoft applications and mobile platforms, with ability to adapt and leverage emerging technologies, such as artificial intelligence, to improve efficiency, automation, and collaboration.

Responsibilities

• Perform analytical method validation and characterization independently to support process improvement, product transfer, or new product realization projects.
• Lead investigations of Out of Specification (OOS) results and nonconformances, identifying root causes and corrective actions.
• Draft, review, and revise QC procedures, including SOPs, protocols, and inspection plans, ensuring compliance with documentation policy.
• Act as lead analyst for complex QC testing of raw materials, intermediates, and final products.
• Mentor and train QC Analytical Scientist 1 and 2 staff in laboratory methods, instrumentation, and good documentation practices.
• Maintain and troubleshoot QC Lab instrumentation and associated analytical methods for product release testing.

Skills

Analytical instrumentation knowledge

Statistical analysis

Mentoring / Training

Digital tools / AI

Education

BS in Chemistry or related field

MS in Chemistry or related field

Tools

Analytical instrument suite (HPLC, LC-MS, GC, NMR, ICP-MS)

Job description

Promega in Madison, WI seeks a QC Analytical Scientist 3 to perform complex analytical testing for API release and stability; participate in method development, validation, and training. You will be a key team member applying chemistry knowledge to support QC and manufacturing.

You will validate methods, lead OOS investigations, draft QC procedures, mentor junior staff, maintain instrumentation, and leverage digital tools including AI to improve efficiency and compliance.