Lead Purification Process Scientist – Biologics

Denali Therapeutics Inc; South San Francisco (CA); On-site; USD 159,000 - 207,000; Full time

Benefits offered by this job

401(k)

Healthcare coverage

Employee Stock Purchase Plan (ESPP)

Job summary

Denali Therapeutics Inc in South San Francisco is seeking a Scientist to lead purification processes for large molecule pipelines. The candidate will develop protocols and validate methods while collaborating across teams. A PhD in a relevant field and over 10 years of experience are required, along with expertise in purification techniques and analytics.

The position offers a compensation range from $159,000 to $207,000, along with a comprehensive benefits package.

Qualifications

• Typically requires a PhD in Biology, Biochemistry, Chemical Engineering or related discipline, plus 10+ years of related experience.
• Experience with purification process characterization and validation.
• Proven track record of working effectively with CMOs.

Responsibilities

• Lead purification/downstream process characterization and tech transfer.
• Author protocols and coordinate study execution.
• Design lab-scale chromatography and filtration studies.

Skills

Purification process characterization

Analytical techniques (ELISA, HPLC)

Bioprocess representation

Critical thinking and problem-solving

Communication skills

Education

PhD in Biology, Biochemistry, or Chemical Engineering

Tools

AKTA protein purification systems

HPLC

LC/MS

SDS-PAGE

Job description

Denali Therapeutics Inc in South San Francisco is seeking a Scientist to lead purification processes for large molecule pipelines. The candidate will develop protocols and validate methods while collaborating across teams. A PhD in a relevant field and over 10 years of experience are required, along with expertise in purification techniques and analytics.

The position offers a compensation range from $159,000 to $207,000, along with a comprehensive benefits package.