Lead Principal Statistician (Remote Europe)

Syneos Health, Inc.; United States; Remote; USD 101,000 - 146,000; Full time

Job summary

Syneos Health is seeking a Principal Statistician for Early Phase, fully remote in Europe. The role leads the development of clinical strategies and statistical plans across trials, mentoring biostatisticians and providing expert input into SAPs and regulatory submissions.

You will collaborate with sponsors, design trials, and ensure timely, high-quality deliverables, while communicating complex statistics clearly to cross-functional teams.

Qualifications

• Master's degree in biostatistics or related discipline is required.
• Extensive experience leading multiple projects and programs of clinical studies.
• Proficiency in R programming and strong statistical design expertise.
• Experience with regulatory submissions is preferred.
• Excellent written and verbal communication skills are essential.
• Ability to communicate statistical concepts effectively to cross-functional teams.

Responsibilities

• Leads development and execution of a clinical development plan, including Go/No Go framework.
• Uses simulations and statistical strategy to inform trial design decisions.
• Mentors biostatisticians and oversees training of team members.
• Directs activities of biostatistics personnel to ensure on-time, high-quality work.
• Prepares SAPs and supports programming for tables, listings, figures.
• Collaborates with sponsors and may lead as Lead Biostatistician on protocols.
• Provides input to regulatory submissions and CSR documentation.

Skills

Statistical design

Clinical trial leadership

R programming

Regulatory knowledge

Communication skills

Programming for CSR

Education

Master's degree in biostatistics

Tools

R

Job description

Syneos Health is seeking a Principal Statistician for Early Phase, fully remote in Europe. The role leads the development of clinical strategies and statistical plans across trials, mentoring biostatisticians and providing expert input into SAPs and regulatory submissions.

You will collaborate with sponsors, design trials, and ensure timely, high-quality deliverables, while communicating complex statistics clearly to cross-functional teams.