Lead, Nonclinical & Translational Oncology Research

UroGen Pharma, Inc.; Pennsylvania; On-site; USD 180,000 - 260,000; Full time

Benefits offered by this job

Medical

Dental

Vision

401k Match

PTO

Employee Assistance Program

Job summary

UroGen Pharma, Inc. is seeking an accomplished scientist to serve as Associate Director/Director of Nonclinical and Translational Research. You will lead nonclinical and translational activities supporting oncology programs and contribute to IND submissions.

The role offers in-person collaboration in Philadelphia and potential progression to director level based on experience. The ideal candidate has a Ph.D.

Qualifications

• Ph.D. in cell biology, immunology, or virology or related discipline.
• Expertise in tumor immunology and/or virology.
• At least five years of relevant biotechnology or pharmaceutical industry experience.
• Experience leading nonclinical and/or translational cancer drug discovery or development programs.
• Direct experience drafting nonclinical sections of IND submissions.
• Demonstrated success managing outsourced research relationships.
• Strong understanding of nonclinical studies and regulatory requirements to advance programs into and through clinical development.
• Strong scientific judgement, collaboration, and written and verbal communication skills.
• Ability and willingness to work regularly in person in Philadelphia.

Responsibilities

• Lead nonclinical and translational research activities aligned with program, clinical development, and regulatory objectives.
• Design and oversee in vitro and in vivo studies evaluating mechanism of action, pharmacology, efficacy, and/or biodistribution.
• Select and manage vendors and consultants, including study design, protocol development, data review, troubleshooting, and final reports.
• Lead preparation of nonclinical sections of IND submissions and other regulatory documents and partner with nonclinical safety/toxicology to integrate findings.
• Evaluate clinical pharmacodynamic and predictive biomarker data to assess biological activity, inform dosing regimen and/or patient selection, and guide program decisions.
• Support scientific due diligence and evaluation of licensing, partnering, and other business development opportunities.

Skills

Tumor immunology

Nonclinical/translational leadership

IND submissions drafting

Vendor management

Cross-functional collaboration

Written/verbal communication

In-person collaboration (Philadelphia)

Education

Ph.D. in cell biology, immunology, or virology

Job description

UroGen Pharma, Inc. is seeking an accomplished scientist to serve as Associate Director/Director of Nonclinical and Translational Research. You will lead nonclinical and translational activities supporting oncology programs and contribute to IND submissions.

The role offers in-person collaboration in Philadelphia and potential progression to director level based on experience. The ideal candidate has a Ph.D.