Lead Mass Spectrometry Scientist - Vaccine Proteomics

Merck; West Point (PA); On-site; USD 157,000 - 247,000; Full time

Job summary

Merck in West Point, PA seeks a Principal Scientist with leadership in mass spectrometry to advance vaccine development and analytical excellence. You will guide a team of scientists, design experiments, and collaborate across programs to accelerate pipeline progress.

The role emphasizes MS-based protein characterization, proteomics, data science, and mentoring junior staff, with opportunities to present findings and influence strategic decisions.

Qualifications

• PhD in Analytical Chemistry or related mass spectrometry field with 10+ years in pharma.
• Expertise designing and conducting MS/proteomics experiments, including sample prep, MS operation and data analysis.
• Knowledge of Thermo, Sciex, and Waters platforms.
• Strong verbal and written communications evidenced by publications.
• Experience mentoring junior scientists in pharmaceutical development.

Responsibilities

• Lead a group of junior scientists delivering MS data to advance the pipeline.
• Advance MS methods for peptide mapping, intact mass, native mass, HDX, and glycan analysis.
• Represent the MS group in project teams.
• Author technical reports and presentations.
• Champion compliance and safety as a leader in the lab.

Skills

Mass spectrometry

Proteomics

Data science

Leadership

Project management

Analytical chemistry

Education

PhD in Analytical Chemistry or related mass spectrometry field

Tools

Thermo instruments

Sciex instruments

Waters instruments

Job description

Merck in West Point, PA seeks a Principal Scientist with leadership in mass spectrometry to advance vaccine development and analytical excellence. You will guide a team of scientists, design experiments, and collaborate across programs to accelerate pipeline progress.

The role emphasizes MS-based protein characterization, proteomics, data science, and mentoring junior staff, with opportunities to present findings and influence strategic decisions.