Lead, Liquid Profiling & Genomics (Oncology)

Caris Molecular Pathology; Phoenix (AZ); On-site; USD 140,000 - 190,000; Full time

Job summary

Caris Life Sciences seeks an Assistant Laboratory Director, Liquid Profiling, to lead the operational, scientific, and regulatory oversight of the Liquid Profiling Laboratory. You will help develop and validate advanced molecular assays, including ctDNA, NGS, and PCR-based tests, ensuring high-quality oncology testing for national and international clients.

Collaborate with pathologists, biologists, bioinformatics, and clinical teams to ensure accurate reporting and compliance with CAP/CLIA and

Qualifications

• PhD in Genetics, Molecular Biology, Genomics, or related field.
• ABMGG certification in Laboratory Genetics and Genomics or Clinical Molecular Genetics and Genomics.
• At least three years of post-fellowship experience in a clinical genomics laboratory, preferably focused on molecular oncology.
• Strong understanding of molecular genetics, genomics, and precision oncology principles.
• Experience with molecular diagnostic technologies including NGS, PCR, sequencing, and data interpretation.
• Knowledge of CAP, CLIA, NYS DOH, and/or ISO 15189 regulatory requirements.
• Excellent written and verbal communication skills.
• Ability to work collaboratively in a multidisciplinary environment.
• Residency in or willingness to relocate to the Phoenix, AZ area is required.

Responsibilities

• Supports laboratory leadership in ensuring quality, compliance, and clinical integrity of high-complexity molecular testing services.
• Assists Laboratory Director in oversight of high-complexity molecular testing operations in compliance with CAP, CLIA, NYS DOH, ISO 15189, and other regulatory requirements.
• Supports implementation, development, validation, verification, and ongoing performance monitoring of molecular oncology assays, including liquid biopsy platforms, NGS, fragment analysis, and PCR-based assays.
• Evaluates, reviews, and interprets genomic profiles and molecular testing data generated from DNA and RNA sequencing analyses.
• Participates in development and maintenance of laboratory quality systems and QA/QC programs.
• Assists in ensuring testing systems provide quality across pre-analytic, analytic, and post-analytic phases.
• Supports documentation and maintenance of laboratory policies, procedures, and regulatory compliance.
• Participates in inspections, audits, proficiency testing, and accreditation activities.

Skills

Team collaboration

Analytical thinking

Problem solving

Communication (written)

Communication (verbal)

Organizational skills

Education

PhD in Genetics, Molecular Biology, Genomics, or related scientific field

ABMGG certification in Laboratory Genetics and Genomics or Clinical Molecular Genetics and Genomics

Job description

Caris Life Sciences seeks an Assistant Laboratory Director, Liquid Profiling, to lead the operational, scientific, and regulatory oversight of the Liquid Profiling Laboratory. You will help develop and validate advanced molecular assays, including ctDNA, NGS, and PCR-based tests, ensuring high-quality oncology testing for national and international clients.

Collaborate with pathologists, biologists, bioinformatics, and clinical teams to ensure accurate reporting and compliance with CAP/CLIA and