Lead Epilepsy Research Scientist

JAX

Bar Harbor (ME)

On-site

USD 136,000 - 212,000

Full time

14 days+
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Benefits offered by this job

Base salary + bonus
Equity
Medical, dental, vision
PTO
Conference attendance support

Job summary

JAX seeks a Lead Scientist to advance epilepsy research within Rare Disease Research. You will spearhead in vivo mouse models and ex vivo brain slice work, generate pivotal datasets, and mentor early-career scientists.

The role integrates pharmacology and translational aims to align preclinical findings with therapeutic hypotheses. You will design dose–response and time-course studies, contribute to IND-enabling efforts, and lead collaborations across disciplines while shaping the direction of

Qualifications

  • PhD in Neuroscience, Pharmacology, Physiology, or a closely related discipline.
  • Minimum 8 years of post-doctoral research with epilepsy or seizure biology.
  • Expert-level in in vivo electrophysiology and brain slice methods.
  • Strong publication record in related CNS fields.

Responsibilities

  • Design, execute, and lead seizure studies in mouse epilepsy models.
  • Lead in vivo electrophysiology and ex vivo slice experiments; mentor staff.
  • Drive preclinical therapeutic development and regulatory-ready data packages.
  • Collaborate across chemistry, pharmacology, and translational teams.

Skills

In vivo electrophysiology
Brain slice electrophysiology
Preclinical drug development
Scientific leadership
Data analysis

Education

PhD in Neuroscience or related field

Tools

Clampfit
Spike2
MATLAB
Python

Job description

JAX seeks a Lead Scientist to advance epilepsy research within Rare Disease Research. You will spearhead in vivo mouse models and ex vivo brain slice work, generate pivotal datasets, and mentor early-career scientists.

The role integrates pharmacology and translational aims to align preclinical findings with therapeutic hypotheses. You will design dose–response and time-course studies, contribute to IND-enabling efforts, and lead collaborations across disciplines while shaping the direction of

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