Lead Clinical Research Data Manager

The University of Chicago; Chicago (IL); On-site; USD 65,000 - 80,000; Full time

Benefits offered by this job

Benefits eligible

Job summary

The University of Chicago is seeking a Lead Clinical Research Data Manager to oversee high‑complexity data tasks in support of PI‑driven studies. You will ensure protocol adherence, data quality, and proper documentation across research projects.

The role requires advanced data management skills, experience with EDC systems (RAVE, Inform, REDCap), and the ability to supervise a small team while maintaining confidentiality and regulatory compliance.

Qualifications

• Education: college/university degree in related field.
• 5-7 years of work experience in a related discipline.
• Bachelor's degree preferred for advanced roles.

Responsibilities

• Leads and oversees data management tasks for high-complexity clinical studies with minimal oversight.
• Manages document collection/review with PI, maintaining confidentiality.
• Conducts quality assurance reviews requested by sponsors or agencies.
• Oversees study documentation for analysis and regulatory reports; identifies trends needing action.
• May supervise 1-2 data managers and provide performance feedback.
• Leads recruitment for new positions and related activities.

Skills

Data management

Analytical skills

Excel pivot tables

EDC systems familiarity

Confidentiality

Multi-tasking

Education

Bachelor's degree

Related field degree

Tools

RAVE

Inform

REDCap

Excel

Word

Adobe Acrobat

Job description

About the Department

Department BSD MED - Hematology and Oncology - Clinical Research Data Managers

About the Department The Section of Hematology/Oncology has a proud and long tradition of excellence in research-based patient care and clinical discovery. Ranked among the finest cancer programs in the country, the Section is comprised of nationally and internationally known faculty with expertise in all major types of malignancies, blood disorders, and experimental therapies.

Job Summary

The Lead Clinical Research Data Manager will perform a variety of data management duties of a complex and technical nature in support of clinical research studies conducted by principal investigators (PIs) for the clinical research program to ensure adherence to protocols and quality of information received.

Responsibilities

• Leads and oversees all data management tasks in support of high-complexity clinical research studies with no oversight.
• Manages document collection and review in collaboration with the principal investigator (PI) while maintaining a high degree of confidentiality.
• Directs quality assurance reviews conducted by study sponsors, federal agencies, or specially designated internal review groups.
• Oversees study-related documentation for analysis, such as protocol worksheets, adverse event reports, institutional review board documents, or progress reports, while identifying operational trends that require corrective actions.
• May supervise 1-2 data managers.
• Assesses and balances workload, assigns studies, and provides feedback on performance.
• Leads recruitment for new positions.
• Performs other related work as needed.

Minimum Qualifications

Education: Minimum requirements include a college or university degree in related field.

Work Experience: Minimum requirements include knowledge and skills developed through 5-7 years of work experience in a related job discipline.

Certifications: ---

Preferred Qualifications

Education: Bachelor's degree.

Experience: 5 years of research experience with 3 years in clinical research.

Technical Skills or Knowledge

Advanced data management skills, including oversight of database design, complex data integration across multiple sources, identification of discrepancies, and implementation of quality control measures to support clinical research. Advanced proficiency in Microsoft Word, Excel, and Adobe Acrobat, including managing large datasets using pivot tables and complex formulas, generating automated reports, and preparing regulatory-compliant documents. Familiarity with common electronic data capture systems such as RAVE, Inform, and RedCap.

Preferred Competencies

• Strong analytical skills.
• Handle competing demands with diplomacy and enthusiasm.
• Strong data management skills.
• Work collaboratively and with divisional research offices.
• Maintain a high degree of confidentiality with clinical data and client's proprietary data.
• Adapt to changing working situations and work assignments.
• Work independently and as part of a team.
• Strong attention to detail.
• Excellent multi-tasking skills.

Job Family

Research Role Impact Individual Contributor

Scheduled Weekly Hours 37.5

Drug Test Required No Health Screen Required No Motor Vehicle Record Inquiry Required

No Pay Rate Type Salary FLSA Status Exempt

Pay Range $65,000.00 - $80,000.00 The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.

Benefits

Benefits Eligible Yes

The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.

Posting Statement

The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

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The University of Chicago is an urban research university that has driven new ways of thinking since 1890. Our commitment to free and open inquiry draws inspired scholars to our global campuses, where ideas are born that challenge and change the world. We empower individuals to challenge conventional thinking in pursuit of original ideas. Students in the College develop critical, analytic, and writing skills in our rigorous, interdisciplinary core curriculum. Through graduate programs, students test their ideas with UChicago scholars, and become the next generation of leaders in academia, industry, nonprofits, and government.

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