Lead, Clinical Pharmacology for Oncology ADCs

SystImmune, Inc.; Princeton (NJ); On-site; USD 150,000 - 200,000; Full time

Benefits offered by this job

Comprehensive benefits package

Equal Opportunity Employer

Job summary

SystImmune, Inc. is seeking a Senior Manager/Associate Director of Clinical Pharmacology to lead the development and execution of pharmacology strategies for ADC assets in a oncology-focused portfolio.

You will direct PK/PD analyses, dose optimization, and regulatory filings while collaborating with Clinical, Research, Regulatory, and Biometrics teams in Princeton, NJ and nearby sites. The role requires extensive experience in clinical pharmacology, pharmacometrics, and drug interaction

Qualifications

• MS/PharmD/PhD in biology or pharmaceutical sciences with focus on pharmacology and pharmacometrics.
• Understanding of clinical pharmacology study design, data analysis and regulatory requirements.
• Minimum 1–5 years of experience in clinical pharmacology and pharmacometrics with hands-on quantitative analysis.
• Prior experience in ADC development is a plus.

Responsibilities

• Plan and conduct oncology clinical pharmacology studies with complex scope.
• Guide dose, schedule and drug‑drug interaction considerations with cross‑functional colleagues.
• Perform quantitative pharmacology analyses and interpret results across development phases.
• Lead pharmacometrics analyses to support development and address scientific questions.
• Prepare and review clinical pharmacology sections of study protocols, reports, investigators' brochures and regulatory filings.

Skills

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Pharmacometric modelling

MIDD (model-informed drug development)

Data analysis

Education

MS/PharmD/PhD in biological or pharmaceutical sciences

Tools

NONMEM

R

Simcyp

WinNonlin

Job description

SystImmune, Inc. is seeking a Senior Manager/Associate Director of Clinical Pharmacology to lead the development and execution of pharmacology strategies for ADC assets in a oncology-focused portfolio.

You will direct PK/PD analyses, dose optimization, and regulatory filings while collaborating with Clinical, Research, Regulatory, and Biometrics teams in Princeton, NJ and nearby sites. The role requires extensive experience in clinical pharmacology, pharmacometrics, and drug interaction