Lead Agentic AI Scientist — Data Science Office

St. Jude Children's Research Hospital; Memphis (TN); On-site; USD 86,000 - 155,000; Full time

Job summary

St. Jude Children’s Research Hospital in Memphis, TN seeks an Agentic AI Scientist in the Office of Data Science to lead the design, development, and evaluation of agentic AI systems that support research and operations.

You will build and orchestrate LLM-based agents, develop secure, interoperable infrastructure, and translate emerging AI capabilities into practical, high-impact solutions while guiding staff and contributing to technical reporting and results evaluation.

Qualifications

• Minimum: Bachelor's in Computer Science, Bioinformatics, Biomedical Engineering, or a related field with 6+ years of relevant experience (OR) Master's with 4+ years (OR) entry-level PhD with no work experience. PhD requirement waived, given an extraordinarily unusual level of scientific contribution.
• Publication benchmark: 1 to 2 first-author papers with a journal impact factor > 5 (or equivalent contribution to other research / open-source outputs).
• Preferred: prior applied-ML or agentic-AI research; demonstrated shipping of LLM-integrated systems; healthcare, biomedical, or other research-intensive domain experience.
• Experience in project coordination, maintenance, and other research support activities preferred.

Responsibilities

• Lead computationally focused agentic-AI research and engineering projects with moderate supervision from the manager; provide inputs on analytical approaches, set up experiments, and develop new agentic methods with manager input.
• Design and orchestrate agent systems (agent hierarchies, tool use, handoffs, checkpointing, and human-in-the-loop control) over ODS data and tools.
• Stand up and maintain MCP servers/clients and A2A-interoperable agents that connect ODS assets (e.g., St. Jude Cloud, internal warehouses, planning systems) under secure, auditable, HIPAA-aligned patterns.
• Identify, process, organize, summarize, review, and report results; instrument every agent with tracing, evaluations, and cost/latency budgets.
• Draft manuscripts and technical reports and work through submission and internal review with manager input; instruct and guide other staff in agentic-AI techniques.
• Mentor others in agentic AI best practices and standards

Skills

Agent frameworks

Interoperability

Orchestration

Observability

Security

Python programming

Education

Bachelor's in CS

Master's in related field

PhD (entry-level waived)

Tools

LangGraph

OpenAI Agents SDK

Google ADK

CrewAI

Pydantic AI

LlamaIndex

Haystack

DSPy

Job description

St. Jude Children’s Research Hospital in Memphis, TN seeks an Agentic AI Scientist in the Office of Data Science to lead the design, development, and evaluation of agentic AI systems that support research and operations.

You will build and orchestrate LLM-based agents, develop secure, interoperable infrastructure, and translate emerging AI capabilities into practical, high-impact solutions while guiding staff and contributing to technical reporting and results evaluation.