LC-MS/MS Scientist (MS/PhD Preferred)

Endless Health; Austin (TX); On-site; USD 65,000 - 100,000; Full time

Benefits offered by this job

Meaningful equity options

Job summary

A healthcare diagnostics company seeks a Mid-Senior Level Scientist to develop and validate quantitative LC-MS/MS methods for clinical programs. The ideal candidate will bring an MS or PhD in Analytical Chemistry or related fields, with 2–5+ years LC-MS/MS experience in regulated environments. This full-time role offers meaningful equity, allowing team members to share in its success. Join a fast-moving team dedicated to impactful healthcare solutions, and contribute directly to scientific advancements.

Qualifications

• 2–5+ years hands-on LC-MS/MS experience in regulated clinical or bioanalytical environments.
• A proven track record in quantitative assay development on triple quads.
• Strong practical mindset, caring about scientific rigor.

Responsibilities

• Develop, optimize, and validate quantitative LC-MS/MS methods.
• Own sample prep workflows for serum/plasma and DBS/card matrices.
• Mentor and train junior analysts to raise standards.

Skills

Quantitative assay development

LC-MS/MS experience

Mentoring and training

Analytical Chemistry

Education

MS or PhD in Analytical Chemistry or related fields

Tools

SCIEX 7500+

UHPLC systems

Job description

💰 Salary range: $65,000 – $100,000 USD per year (depending on experience)

📈 Meaningful equity options included

About EndlessDx Laboratory (www.endlessdx.com)

At EndlessDx, we’re building a clinical lab that marries analytical rigor with real‑world impact. We’re CLIA/CAP-accredited and laser‑focused on delivering high‑quality LC‑MS/MS assays for screening and clinical programs that can change how preventive and precision medicine reach patients.

We’re a small, fast‑moving team that values speed, frugality, hard work, deep technical growth and mastery, clever experimental design, and smart, practical science. If you love developing robust methods and want your work to power actual patient care—not sit on a shelf—this is the place.

What You’ll Do

• Develop, optimize, and validate quantitative LC‑MS/MS methods (triple quadrupole) to CLIA/CAP standards.
• Own sample prep workflows (PP, LLE, SPE; steroid derivatization) for serum/plasma and DBS/card matrices.
• Run and maintain SCIEX 7500+ and UHPLC systems, troubleshooting real issues like suppression, interferences, and carryover.
• Write and execute validation plans, SOPs, and study reports; ensure complete data integrity and traceability through L.screen>
• Mentor and train junior analysts, helping to raise the collective bar on analytical science in the lab.

What You Bring

• MS or PhD in Analytical Chemistry They Biochemistry, Pharmaceutical沒有, or related fields (BS with strong experience considered).
• 2–5+ years hands zoektocht LC‑MS/MS experience in regulated clinical or bioanalytical environments.
• A proven track record in quantitative assay development on triple quads—stable isotope IS use, calibration/QC strategy, clean data under pressure.
• A builder’s mindset: you care about scientific rigor, but you’re also practical and love seeing your assays go live.

Bonus Points For

• Experience with neuro proteins, neuropharmacological, hormone/steroid panels, PFAS, or blood biomarker assays.
• DBS workflows expertise (e.g., hematocrit/matrix effect mitigation).
• Exposure to CLIA/CAP inspections, CLSI guidelines, or other regulated validation frameworks.

Why This Role Matters

Our LC‑MS/MS lab is the beating heart of how we deliver precision diagnostics at scale. The methods you build will directly power clinical programs, sometimes weeks after you validate them. You’ll get to shape both the science and the systems in a modern, well‑equipped lab—working alongside a small, sharp team that辦移cribes fast and sweats the details. You will grow fast and enjoy weekly meetings with both the VP of science and the CEO.

We offer meaningful equity because we want our early team members to share in the upside of人人爽 building something important and enduring.

িফর ল্যান্ট
🔗 Interested? Apply via LinkedIn with a statement of interest at the top of symptom your CV (Why are you interested in this role at Endless) or email your CV with that statement directly to w [e-mail]. If you’re the kind of scientist who lights up talking about signal suppression or calibration curve residuals, we should talk.

Seniority level

Mid‑Senior level

Employment type

Full‑time

Job function

Research, Analyst, and Information Technology

Industries

-interactice LNHealth and Personal Care Products